Although NK cells are also cytolytic effector cells, the role of this marker has not been addressed for this subset of lymphocytes. Here, we assessed whether CD107a was expressed on the surface of NK cells following stimulation. Freshly isolated PBMCs were incubated with MHC devoid target cells...
A Modified NK Cell Degranulation Assay Applicable for Routine Evaluation of NK Cell Function (LAMP-1, CD107a) is a marker for degranulation of NK and cytotoxic T cells and its expression is a sensitive marker for the cytotoxic activity ... S Snehal,G Maya,M Manisha - Journal of Immunology...
We read with interest, in a recent issue of Leukemia, the paper by Penack et al1 about the validation of CD107a as a functional marker for natural killer (NK) cell activity. As in cytotoxic T cells, CD107a was shown by flow cytometry to be expressed at the cell surface as a conseq...
Various aberrancies have been described in CLL cases, including abnormal (dim or bright) expression of B cell markers and lineage infidel T cell, myelomonocytic, or rarely Natural killer (NK) cells markers. However, the aberrant co-expression of CD56 and CD57 has not yet been reported. ...
antigen is found on erythrocytes, B cells, a subset of T cells, monocytes, as well as eosinophils, and neutrophils. Anti-CD35 is considered a mature B-cell marker which labels follicular dendritic reticulum cells and tumors derived from such cells such as follicular dendrit...
All NK cells express the lymphocyte marker CD7. The CD56+dim NK cells can be divided into subpopulations based upon CD2 expression. CD2 is the ligand for lymphocyte function–associated antigen-3 (LFA-3, or CD58) [10]. CD8, also present on the cytotoxic population of T cells, is ...
and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b in...
CD107a as a functional marker for the identification of natural killer cell activity. J Immunol Methods 2004; 294: 15–22. Article CAS Google Scholar Schmidt RE, Murray C, Daley JF, Schlossman SF, Ritz J . A subset of natural killer cells in peripheral blood displays a mature T cell ...
Fig. 3 Treatment with anti-CD24 mAb promotes phagocytic clearance of human cancer cells 写在最后 CD24在多种实体癌中均为高表达的抗吞噬信号,本文所引研究数据让我们看到阻断CD24在癌症免疫治疗中的潜力。基于“别吃我(Don't eat me)”信号蛋白,阻断CD24—siglec10有望能够超越PD-L1、CD47、B2M这些已开...
and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases dur...