Markers and function of human NK cells in normal and pathological conditions. Cytometry Part B: Clinical Cytometry.Del Zotto G, Marcenaro E, Vacca P, Sivori S, Pende D, Della Chiesa M, et al. Markers and function of human NK cells in normal and pathological conditions. Cytometry B Clin ...
主要参考文献 1. Donne Estipona,A Guide to NK Cell Markers:An overview of proteins used in identifying natural killer cells, https://www.biocompare.com/Editorial-Articles/576304-A-Guide-to-NK-Cell-Markers/ 2. Cooper MA, Fehniger TA, Caligiuri MA. The biology of human natural killer-cell ...
自然杀伤细胞(Natural killer cell,NK)是主要的先天淋巴细胞亚群,被认为是人体健康的第一道防线。可以介导多种免疫反应,包括免疫监视和清除衰老细胞。 近期,国际期刊《Biochemistry and Biophysics Reports》中的一篇题为“Autologous NK cells propagated ...
国际期刊《Biochemistry and Biophysics Reports》中的一篇题为“Autologous NK cells propagated and activated ex vivo decrease senescence markers in human PBMCs”的研究论文,发现经扩增培养的自体NK细胞,除了表现出很强的杀肿瘤细胞和清除衰老细胞的能力,而且在输注后降低了血液中外周血单个核细胞(PBMC)的衰老标记...
近期,国际期刊《Biochemistry and Biophysics Reports》中的一篇研究论文Autologous NK cells propagated and activated ex vivo decrease senescence markers in human PBMCs,发现经扩增培养的自体NK细胞,除了表现出很强的杀肿瘤细胞和清除衰老细胞的能力,而且在回输后降低了血液中PBMC的衰老标记物。
Human NK Cells Expanded using the CellXVivo™ Kit Express NK Cell-specific Markers.Human NK cells were enriched from peripheral blood mononuclear cells and expanded (3 x 106starting population) using the CellXVivo™NK Cell Expansion Kit (A, C, E) or by the standard method using artificial...
we review the associations between human diseases and mutations in genetic elements affecting natural killer (NK) cell development and function. Although many such genetic aberrations significantly reduce NK cell numbers or severely impair NK cell responses, inferences regarding the role of NK cells in...
Expression of NK cell markers on infant intestinal NK cells ILCs are a heterogeneous population with different effector functions6,9,10,12,17. The lack of a hallmark lineage marker to distinguish NK cells from other ILC1s in tissues has led to conflicting results investigating ILCs10,22,23,24...
While distinct stages of natural killer (NK) cell development have been defined, the molecular interactions that shape human NK cell maturation are poorly understood. Here we define intercellular interactions between developing NK cells and stromal cells
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