中文名称:NK-92 Cell Lines:人恶性非霍奇金淋巴瘤患者NK细胞(STR认证) 英文名称:NK-92 Cell Lines 保存条件: 常温培养或液氮冻存 纯度规格: NK-92 Cell Lines:人恶性非霍奇金淋巴瘤患者NK细胞(STR认证) 产品类别: 生物试剂 "NK-92 Cell Lines:人恶性非霍奇金淋巴瘤患者NK细胞(STR认证) 细胞背景资料:NK细胞...
The NK-92 cell line was initially EBV negative, but over time acquired the virus although no active virions are produced. These cell lines have become useful to investigators to study the biology of NK cells and NK lymphomas/leukemias. The only NK cell line that has undergone extensive ...
中文名称:NK-92MI cell line人恶性非霍奇金淋巴瘤患者NK细胞系 英文名称:NK-92MI cell line 保存条件: 低温避光 纯度规格: 1x10(6)viable cells/ml 产品类别: 有机化学品 "NK-92MI cell line人恶性非霍奇金淋巴瘤患者NK细胞系 细胞背景资料:NK细胞;淋巴瘤;男性 细胞的衰老:体外细胞培养实验证明:成纤维细胞...
另一方面提供一种增殖nk细胞的方法,包括收获含有混合的nk细胞(mixed immune cells)群的血液样品;以及使所述混合的nk细胞群的至少一部分与用于激活nk细胞的经基因改造的细胞接触,其中,所述经基因改造的细胞经基因改造以表达膜结合白细胞介素-18(membrane bound interleukin-18:mbil-18)、膜结合白细胞介素-21(membran...
Mechanistic studies revealed that membrane-bound IL-21 leads to an activation of a STAT3/c-Myc pathway and increased NK cell metabolism with a shift towards aerobic glycolysis. The NKF feeder cell line is a promising new platform that enables the large scale proliferation of highly active NK ...
As expected, Ki67 levels are higher when either feeder cell line is used as compared to IL-2-NK cells (p = 0.0021) (Fig. 4A). Figure 4 mbIL-21 signaling promotes increased metabolic activity in NKF-NK cells but does not affect cytotoxicity. (A) NKF cells lead to enhanced NK ...
( 3 x 106starting population) using the CellXVivo™NK Cell Expansion Kit or by the standard method using artificial antigen-presenting K562 clone 9.mbIL-21 cells. After 14 days of expansion, NK cells were assessed for CD16 expression. NK cell expanded using the CellXVivo™Kit expressed ...
21. Renaissance of armored immune effector cells, CAR-NK cells, brings the higher hope for successful cancer therapy. [PMID: 33752707]22. Overcoming Resistance to Natural Killer Cell Based Immunotherapies for Solid Tumors. [PMID: 30805309]23. Anti-PSMA CAR-Engineered NK-92 Cells: An Off-...
Finally, a NK cell line engineered to express a chimeric receptor encompassing the extracellular domain of transforming growth factor beta receptor 2 (TGFBR2) fused to the intracellular domain of NKG2D has recently been shown to mediate superior therapeutic efficacy in preclinical HCC models, ...
NK Cell-Mediated Killing of DC Once activated, NK cells recruited to sites of inflammation, acquire the capability of killing immature myeloid DCs.18–21 This effect is due to the fact that immature DCs typically underexpress HLA-class I molecules that would protect from NK-mediated lysis. On...