Basic Information 英文标题: NIR-II light in clinical oncology: opportunities and challenges 中文标题:临床肿瘤学中的NIR-II光:机遇与挑战 发表日期:01 May 2024 文章类型:Review Article 所属期刊:Nature Reviews Clinical Oncology 文章作者:Zeyu Zhang | Jie Tian 文章链接:https://www.nature.com/articles/s...
2024年5月1日,北京航空航天大学工程医学院的Jie Tian研究团队在国际知名期刊《Nature Reviews Clinical Oncology 》发表了题为:NIR-II light in clinical oncology: opportunities and challenges的回顾性文章。该文章综述了第二近红外区域(NIR-II,900-1880纳米波长)在临床肿瘤学中的应用,包括其在癌症手术中的荧光成像...
Furthermore, the use of NIR-II light promises to improve cancer phototherapy by enabling the selective delivery of increased therapeutic energy to tissues at greater depths. Initial clinical studies of NIR-II-based imaging and phototherapy have indicated impressive potential to decrease cancer recurrence...
Owing to reduced light scattering and tissue autofluorescence, in vivo fluorescence imaging in the 1,000–3,000-nm near-infrared II (NIR-II) spectral range can afford non-invasive imaging at depths of millimetres within biological tissue. Infrared fluorescent probes labelled with antibodies or other...
Inorganic agents have the drawbacks of potential long-term safety concerns, poor biodegradation, and unclear metabolic pathways, which restrict their clinical applications [6, 22]. Organic polymeric materials typically absorb radiation in the NIR-II window; however, their poor solubility and metabolism ...
The introduction of lymphoscintigraphy in SLNB is thus far considered the “gold standard” in clinical oncology for assessing and staging breast, melanoma, head and neck cancer metastasis10,11,12. High SLN detection rates were achieved in clinical trials with scintigraphy in conjunction with SPECT/...
To confirm that NIR light could improve peroxidase-like activity, the CBS/H2O2/TMB mixed solution was irradiated with 808 nm laser for 10 min at 0.4 W/cm2, then the absorption of the mixed solution was measured. 2.4. Photothermal performance of CuBiSe in vitro The CBS (1.0 mL) with ...
In a clinic, sometimes tumor resection cannot be performed due to the presence of many smaller tumors or a very large tumor, and multiple treatments are the common treatment methods in clinical practice. Given the strong ROS generation capacity of PTZ-TQ NPs, it was used for PDT of the ...
Near‐infrared (NIR) light‐triggered hyperthermia has exhibited promising prospects in oncology therapy due to the unique merits including minimal invasiveness, monitorable, excellent therapeutic effect, and negligible side effects. Especially, the second NIR biowindow (NIR‐II, 1000–1700 nm) with ...
With salient photostability and a photothermal conversion rate of 55.37%, Se-IR1100 NPs hold promise as a superior photosensitizer for diagnostic and therapeutic agents in oncology. Overall, we have designed and optimized a multifunctional photosensitizer Se-IR1100 with good biocompatibility that performs...