The NHGRI-EBI GWAS Catalog serves as a vital resource for the genetic research community, providing access to the most comprehensive database of human GWAS results. Currently, it contains close to 7 000 publications for >15 000 traits, from which more than 625 000 lead associations...
NHGRI-EBI GWAS目录提供了自2008年以来已发表的全基因组关联研究的数据。2015年,数据库重新设计并迁移到EMBL-EBI。新的数据库拥有一个新的图形用户界面(http://www.ebi.ac.uk/gwas/),支持搜索功能,具有改进的扩展接口。这些发展主要通过自动化管理和尺度缩放方面的改进提高了数据发布频率;可用的目录范围也扩展了,...
MacArthur, Jacqueline, et al. "The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)."Nucleic Acids Research(2016): gkw1133.
The GWAS Catalog delivers a high-quality curated collection of all published genome-wide association studies enabling investigations to identify causal variants, understand disease mechanisms, and establish targets for novel therapies. The scope of the Catalog has also expanded to targeted and exome ...
Here we describe a framework for the accurate and standardized description of sample ancestry, and validate it by application to the NHGRI-EBI GWAS Catalog. We confirm known biases and gaps in diversity, and find that African and Hispanic or Latin American ancestry populations contribute a ...
(2017). A standardized framework for representation of ancestry data in genomics studies, with application to the NHGRI-EBI GWAS Catalog. bioRxiv.