NHGRI-EBI GWAS目录提供了自2008年以来已发表的全基因组关联研究的数据。2015年,数据库重新设计并迁移到EMBL-EBI。新的数据库拥有一个新的图形用户界面(http://www.ebi.ac.uk/gwas/),支持搜索功能,具有改进的扩展接口。这些发展主要通过自动化管理和尺度缩放方面的改进提高了数据发布频率;可用的目录范围也扩展了,...
doi:10.1111/obr.12806Yuvreet KaurDominic X WangHsin-Yen LiuDavid MeyreJohn Wiley and SonsObesity ReviewsBurdett T, Hall PN, Hasting E, et al. The NHGRI-EBI Catalog of published genome-wide association studies. Available at: http://www.ebi.ac.uk/gwas. Ac- cessed December 15, 2015....
Here we describe a framework for the accurate and standardized description of sample ancestry, and validate it by application to the NHGRI-EBI GWAS Catalog. We confirm known biases and gaps in diversity, and find that African and Hispanic or Latin American ancestry populations contribute a ...
A standardized framework for representation of ancestry data in genomics studies, with application to the NHGRI-EBI GWAS Catalogdoi:10.1101/129395Joannella MoralesEmily H. BowlerAnnalisa BunielloMaria CerezoPeggy HallLaura W. HarrisEmma Hastings