The NF2 protein, also known as merlin or schwannomin, is a recently cloned tumour suppressor and is mutated or inactivated in most schwannomas and meningiomas. Homology analysis indicates that merlin is most closely related to members of the protein 4.1 superfamily especially ezrin, radixin and ...
该转录因子被证明可以负向调节神经元分化)、AC005392.2和LINC00485长基因间非蛋白编码 RNA 过表达,以及复发性脑膜瘤中的KIAA2012过表达(编码一种功能未知的未表征蛋白,在兴奋性神经元、脉络丛和其他纤毛细胞类型中高度表达)(proteinatlas.org)。
This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in...
亚细胞定位Cell projection, filopodium membrane; Peripheral membrane protein; Cytoplasmic side. Ruffle membrane; Cytoplasmic side. Nucleu 预测分子量28.6kDa 实际分子量-(差异分析请参阅说明书) 片段与标签Asp30~Leu239 (Accession # P35240) with N-terminal His Tag ...
protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of...
NF2是由染色体22q12上的NF2基因突变所致。NF2 基因编码Merlin蛋白(膜突蛋白-埃兹蛋白-根蛋白样蛋白,即moesin-ezrin-radixin-like protein的缩写)又称为神经膜蛋白。Merlin蛋白涉及细胞膜组建,基于细胞骨架的细胞过程调控,如细胞黏附、迁移、细胞间接触和信号传递等。
神经纤维素2(NF2)重组蛋白 Recombinant Neurofibromin 2 (NF2) ACN; BANF; SCH; Merlin; Bilateral Acoustic Neuroma; Schwannomin; Schwannomerlin; Moesin-Ezrin-Radixin-Like Protein 物种 Homo sapiens (Human
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request. 蛋白标签: N-terminal 6xHis-tagged 产品提供形式: Liquid or Lyophilized powder Note: We will preferentially ship the format that we have in stock, however, if you have ...
Alternate Names NF2; SCH; Merlin; Moesin-ezrin-radixin-like protein; Neurofibromin-2; Schwannomerlin; Schwannomin Description neurofibromin 2(NF2) Homo sapiens This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are though...