p65 Thr505磷酸化负调控多种细胞功能,如增殖、迁移和自噬。Thr505突变将消除p65对肿瘤的抑制功能,导致p65具有促进肿瘤增值和存活的能力。 (Moles A, Butterworth JA, Sanchez A, et al. A RelA(p65) Thr505 phospho-site mutation reveals ...
NFKB3; RELA; TF65; Transcription factor p65; p65; NFkB SwissProt ID Q04206 基因ID 5970 免疫原 Peptide sequence around phosphorylation site of serine 536 (F-S-S(p)-I-A) derived from Human NFκB-p65. 缓冲液 Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH...
Doxorubicin inhibits SIRT2 and NF-kB p65 phosphorylation in Breast cell-line cancerDoxorubicinApoptosisSIRT2-NF-Molecular dockingPredicted gene expressionDoxorubicin induces tumor cell death with an IC50 value of 8,32渭M.Doxorubicin inhibited SIRT2 and the NF-kB p65 (RelA) proteins leading to the ...
免疫原 :KLH conjugated synthesised phosphopeptide derived from human NFKB p65 around the phosphorylation site of Ser311:FK(p-S)IM 亚型:IgG 纯化方法 :affinity purified by Protein A 储存液 :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. ...
细胞核因子k基因结合核因子抗体NFKB p65英文名称:NFKB p65 产品类别:抗体 产品编号:s20106R 产品应用 :WB ELISA IHC-P IHC-F Flow-Cyt ICC IF 性状:Liquid 纯化方法:affinity purified by Protein A 保质期 :1年 保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid...
Target Protein:phospho-NFKB p65 (Thr435) IR:Immunogen Range:EG(p-T)LS Clonality:Polyclonal Isotype:IgG Entrez Gene:5970 Swiss Prot:Q04206 Source:KLH conjugated Synthesised phosphopeptide derived from human NFKBp65 around the phosphorylation site of Thr435:EG(p-T)LS ...
(Nuclear factor kappa-light-chain-enhancer of activated B cells) that heterodimerizes with the other subunits p50 or p52. However, binding of TNF alpha to its cognate receptor phosphorylates IKK which in turn phosphorylates I kB allowing proteasomal degradation of I kB. Phosphorylation of p65 at ...
Target Protein:phospho-NFKB p65 (Thr435) IR:Immunogen Range:EG(p-T)LS Clonality:Polyclonal Isotype:IgG Entrez Gene:5970 Swiss Prot:Q04206 Source:KLH conjugated Synthesised phosphopeptide derived from human NFKBp65 around the phosphorylation site of Thr435:EG(p-T)LS Purification:affinity purified...
The activity of p65-containing NFkB complexes is positively regulated by phosphorylation of the p65 subunit at serine 529.^M^MApplications Reported: This MCFA30 antibody has been reported for use in western blotting, immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, ...
Immunogen DescriptionPeptide sequence around phosphorylation site of threonine 254 (F-R-T(p)-P-P) derived from Human NFkB-p65. Target NameNFkB-p65 ModificationPhospho Alternative NamesNFKB3; RELA; TF65; Transcription factor p65; p65 Accession No.Swiss-Prot: Q04206 ...