Differential role of an NF-魏B transcriptional response element in endothelial versus intimal cell VCAM-1 expression. Circ Res. 2015;117:166-177. doi: 10.1161/ CIRCRESAHA.117.306666.Milstone, D.S.; Ilyama, M.; Chen, M.; O'Donnell, P.; Davis, V.M.; Plutzky, J.; Brown, J.D.;...
A specific double stranded DNA (dsDNA) sequence containing the NF-κB response element is immobilized to the wells of a 96 well plate. NF-κB contained in a nuclear extract, binds specifically to the NF-κB response element. NF-κB (p65) is detected by addition of specific primary antibody...
Activation of nuclear orphan receptor NURR1 transcription by NF-kappa B and cyclic adenosine 5'-monophosphate response element-binding protein in rheumatoid arthritis synovial tissue. Authors: Alice N McEvoy, Eithne A Murphy, Tiia Ponnio … ...
1994: Apo CIII gene transcription is regulated by a cytokine inducible NF-kappa B element Nucleic Acids Research 22(12): 2417-2422 Hayashi, R.; Takemori, T.; Kodama, M.; Suzuki, M.; Tsuboi, A.; Nagawa, F.; Sakano, H. 1997: The PU.1 binding site is a cis-element that ...
Examples of reporter genes indicative of the presence of a protein having a function include reporter genes containing a CREB (cAMP responsive element binding protein) binding sequence or AP-1 (activator protein-1) binding sequence at the expression regulation sequence region of the reporter genes, ...
Results of NF-κB response element luciferase reporter assay confirmed that MB and MZ activated NF-κB. The NF-κB inhibitor (SN50) was also shown to alleviate cytotoxicity induced by co-treatment of MB or MZ and MPP+. This study demonstrates that activation of NF-κB is responsible for ...
Results of NF-kappa B response element luciferase reporter assay confirmed that MB and MZ activated NF-kappa B. The NF-kappa B inhibitor (SN50) was also shown to alleviate cytotoxicity induced by co-treatment of MB or MZ and MPP+. This study demonstrates that activation of NF-kappa B is...
Point mutations in the NF-kappa B site within the 18 bp element disrupt ie1-mediated transactivation and binding. We have found that the characteristics of the 18 bp binding factor from human fibroblasts are indistinguishable from NF-kappa B induced by phorbol ester plus mitogen treatment of T ...
(peroxisome proliferator-activated receptor gamma coactivator1-alpha (PGC-1α), calcium/calmodulin-dependent protein kinase II (CaMKII), cAMP-response element binding protein (CREB), nuclear factor (erythroid-derived 2)-like 2 (Nrf2), early growth response (Egr) factor family of proteins, and ...
Moreover, pp65 was also found in neurites that were immunostained with phosphorylated tau, phosphorylated a-synuclein, or TDP-43 (transactivation response element DNA-binding protein 43 kDa). Therefore, the activation of the NF-kappa B pathway may be related to the pathology of GVD formation ...