NF-kappa B pathwayhuman diseaseIn space, living organisms are exposed to multiple stress factors including microgravity and space radiation. For humans, these harmful environmental factors have been known to cause negative health impacts such as bone loss and immune dysfunction. Understanding the ...
Laboratory Investigation (2016) 96, 1268–1278 © 2016 USCAP, Inc All rights reserved 0023-6837/16 Inhibition of NF-kappa B pathway leads to deregulation of epithelial–mesenchymal transition and neural invasion in pancreatic cancer Alice Nomura1,2, Kaustav Majumder3, Bhuwan Giri1,2, Patricia ...
Figure 3(b) shows significant association between ADAM9 and NF-kappa B in the mRNA expression level (p<0.001).Conclusions:The results clearly showed the activation of PI3K-dependent NF-kappa B pathway triggered by ADAM9. This suggests a novel molecular mechanism that the stable homotrimers of...
NF-kappa B pathway controls mitochondrial dynamics The Optic atrophy 1 protein (OPA1) is a key elemen Weil,R.,Corti,... - 《Cell Death & Differentiation》 被引量: 0发表: 2016年 Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo ummary Mitochondrial abnormalities have been ...
NF-kappa B is a critical nuclear transcriptional factor that is activated in response to cellular stresses and regulates the expression of genes involved in cell proliferation and cell death. When regulated NF-kappa B activation is disrupted, cells undergo apoptosis. That is, constitutively elevated ...
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DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway et al.DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-kappa B pathway,....
Downregulation of DNA-PKcs suppresses P-gp expression via inhibition of the Akt/NF-κB pathway in CD133-positive osteosarcoma MG-63 cells Ka, Li,Xin,etc.Downregulation of DNA-PKcs suppresses P-gp expression via inhibition of the Akt/NF-κB pathway in CD133-positive osteosarcoma MG-63 ... ...
Boldenone (Bdn) and nandrolone (Ndn) are anabolic androgenic steroids (AASs) that, as our previous studies have shown, may increase the risk of neoplastic transformation of porcine ovarian putative stem cells (poPSCs). The NF-κB pathway may be important
It is worth noting, however, that I-BET did not completely abolish cytokine-induced NF-kB activation, as phospho-p65 remained elevated compared to the level observed in unstimulated INS-1 cells. Figure 3. I-BET mediates its effect by antagonizing NF-kB pathway activation. (A,B) The ...