LIGHT and IFN- synergistically reduced MIN6 and primary islet cells viability; decreased cell viability was due to apoptosis, as demonstrated by a significant increase in Annexin V+ cell percentage, detected by flow cytometry. In addition to marked increases in cytochrome c release and NF-B ...
偶联BiotinIFN gamma 抗体:偶联FITCIFN gamma 抗体:偶联HRPIFN gamma 抗体:偶联PE/ATTO 594IFN gamma 抗体:偶联PerCPIFN gamma 抗体:偶联RPEIFN gamma 抗体:偶联StreptavidinIRF3 抗体IRF3 抗体:偶联ATTO 390IRF3 抗体:偶联ATTO 488IRF3 抗体:偶联ATTO 565IRF3 抗体:偶联ATTO 594IRF3 抗体:偶联ATTO 633IRF3 抗体:...
Introduction: Inflammatory bowel disease (IBD) is associated with altered apoptosis and increased levels of Th1 cytokines (IL-12, TNF-α, and IFN-γ). Defects in Stat6, a signal transduction molecule, may lead to increased Th1 effects. We have cell lines derived from IBD patients that express...
CD4+ T cells from p50-/- mice failed to induce Gata3 expression under TH2-differentiating conditions but showed unimpaired T-bet expression and interferon gamma (IFN-gamma) production under TH1-differentiating conditions. Inhibition of NF-kappa B activity prevented GATA-3 expression and TH2 ...
www.nature.com/scientificreports OPEN Transcription factor NF-kappa B represses ANT1 transcription and leads to mitochondrial dysfunctions received: 11 October 2016 accepted: 13 February 2017 Published: 20 March 2017 Chen Zhang1, Hui Jiang2, Pin Wang3, Heng Liu3 & Xiulian Sun4 ...
IFNalpha/beta promotes cell survival by activating NF-kappaB through phosphatidylinositol-3 kinase and Akt p pThe potential mechanisms of action of ozone therapy are reviewed in this paper. The therapeutic efficacy of ozone therapy may be partly due the controll... CH Yang,A Murti,SR Pfeffer,...
Staphylococcal Enterotoxin B Upregulates Expression of ICAM-1 Molecules on IFN-γ-Treated Keratinocytes and Keratinocyte Cell Lines The effects of staphylococcal (), a -derived bacterial superantigen, on expression of intercellular molecule-1 () were examined in cultured normal and tran... H Wakita...
16. Bito T, Roy S, Sen CK, Shirakawa T, Gotoh A, Ueda M, Ichihashi M, Packer L (2002) Flavonoids differentially regulate IFN-γ-induced ICAM-1 expression in human keratinocytes: molecular mechanisms of action. FEBS Lett 520:145–152 Article PubMed CAS Google Scholar 17. Wang YH, Wang...
Interferon-gamma (IFN-gamma) is a pleiotropic lymphokine whose production is restricted to activated T cells and NK cells. Along with other cytokines, IFN-gamma gene expression is inhibited by the immunosuppressant cyclosporin A. We have previously identified an intronic enhancer region (C3) of ...