JNKNF-kappa BTumor necrosis factor-α (TNF-α) is a critical pro-inflammatory cytokine regulating neuroinflammation. At high concentrations, it is toxic to neurons, and such damage is positively correlated with acute and chronic neurological diseases. Our previous studies showed that inhibition of ...
Kaposi’s sarcoma-associated herpesvirus encoded vFLIP induces cellular IL-6 expression: The role of the NF-[kappa]B and JNK//AP1 pathways. Oncogene. 2003; 22 :3371–3385. doi: 10.1038/sj.onc.1206407. [ Cross Ref ]An, J., Sun, Y., Sun, R., Rettig, M.B., 2003. Kaposi's ...
Previous studies have demonstrated a relationship between inflammation, IR and NF-<kappa>B, JNK and ERK pathways [23], [24]. To test whether NF-<kappa>B, JNK and ERK pathway activity changed in rats, we measured the expression of NF-<kappa>B p65, JNK and ERK in the adipose tissue an...
MiR-29b aggravates lipopolysaccharide-induced endothelial cells inflammatory damage by regulation of NF-kappa B and JNK signaling pathways 来自 dx.doi.org 喜欢 0 阅读量: 117 作者:Yuan,Huifeng,Ji,Tengfei,Han,Xinwei 摘要: MicroRNAs (miRNAs) have been reported to involve i 关键词: MicroRNA-29b ...
FAS配体和其他配体与受体结合,用于信号传导途径,例如细胞凋亡或JNK信号传导。受体激动剂经常被用于药物开发,受体是1型、2型或3型配体结合因子和从细胞外接收化学信号的蛋白质分子。当这些化学信号与受体结合或结合时,它们会引起某种形式的细胞/组织反应,例如细胞电活动的改变。从这个意义上说,am嗅觉受体是一种蛋白质...
背景:在肝脏缺血再灌注损伤中,NF-κB 与JNK 通路的串扰方式决定了细胞的死亡或存活。而将低氧预适应用于肝移植过 程所导致的细胞凋亡现象,尚未见有报道。 目的:探讨低氧预适应后NF-κB 的表达对移植肝JNK 通路的影响及保护作用。 方法:采用经门静脉灌注法建立大鼠自体原位肝移植模型,SD 大鼠随机分为正常对照组...
CST 4668S Phospho-SAPK/JNK (Thr183/Tyr185) (81E11) Rabbit mAb 100ul CST 4685 Akt (pan) (11E7) Rabbit mAb 100ul CST 9336S Phospho-GSK-3-beta (Ser9) Antibody 100ul CST 4228S Phospho-PI3K p85 (Tyr458)/p55 (Tyr199) Antibody 100ul 产品留言 标题 联系人 联系电话 内容 验证...
Meanwhile, tyrosol attenuated the released TNF-alpha and IL-6 level from astrocyte via regulating Janus N-terminal kinase (JNK). The reduction of cytokines from astrocyte might be due to its inhibition of astrocyte activation and regulation of STAT3 signaling pathway since tyrosol attenuated the ...
Thrombin caused phosphorylation of p38 MAPK, its substrate ATF-2, and JNK MAPK, but not ERK MAPK. The p38 MAPK inhibitors, SKF86002 and SB-203580 only reduced ATF-2 activity. We treated human umbilical vein endothelial cells with SKF86002, 1 h before thrombin stimulation, and noted ...
186 CST 9252 SAPK/JNK Antibody 200ul 187 CST 2101S Phospho-Src Family (Tyr416) Antibody 100ul 188 CST 2118 GAPDH (14C10) Rabbit mAb 100ul 189 CST 4376S Phospho-p44/42 MAPK (Thr202/Tyr204) (20G11) RmAb (IHC) 200uL 190 CST 4970 beta-Actin (13E5) Rabbit mAb 100ul 191 CST 91...