M.R. Gilbert, New treatments for malignant gliomas: careful evaluation and cautious optimism required, Ann. Intern. Med. 144 (2006) 371-373.Gilbert MR (2006) New treatments for malignant gliomas: careful evaluation and cautious optimism required. Ann Intern Med 144: 371-373...
A new approach to treating the most malignant type of brain cancer - glioblastoma - has shown strong promise in pre-clinical settings, raising hopes of increasing current average survival rates beyond 18 months. Targeted alpha therapy (TAT) is emerging as a potential additional treatment for gliob...
Scientists from the University of Geneva have developed CAR-T cells targeting the PTPRZ1 marker on glioblastoma cells, a promising step toward more effective treatments. These engineered immune cells showed the ability to attack both marked and unmarked tumor cells without harming healthy cells, ...
Generally, Surgery, radiotherapy, and chemotherapy as existing treatments for GBM ultimately increase the patient’s survival by only a few months [7]. New approaches in glioblastoma control The limitations of the effectiveness of existing therapies for GBM and the existence of mechanisms that ...
Glioma is a common primary tumor of the central nervous system (CNS), with glioblastoma multiforme (GBM) being the most malignant, aggressive, and drug resistant. Most drugs are designed to induce cancer cell death, either directly or indirectly, but mal
Treatments for acute lymphoblastic leukemia (ALL) are improving as the overall survival rate at five years from diagnosis raised from 12% in 1960 to 65% in 2014 and around 80% nowadays (1). Unfortunately, in the case of T-cell Acute Lymphoblastic Leukemia (T-ALL), an aggressive subtype of...
So, whereas ad- vances in surgery, radiotherapy, chemotherapy, and as of recently immunotherapy have made therapies mostly safer and somewhat more effective, strong efforts are be- ing made to find new approaches to improve the efficacy of antiglioma treatments. 展开 ...
A team led by Texas A&M University's College of Veterinary Medicine & Biomedical Sciences' (CVM) researcher Dr. Stephen Safe has discovered a new pathway that may help suppress the development of glioblastoma tumors, one of the deadliest forms of can
This study, hence, reviews the current status of immunotherapy among the comprehensive treatments of glioma, at the same time indicates the potential targets of immunotherapy, further to update treatment strategies and explain the the potential for the resistance of immunotherapy. 展开 关键词:...
Glioblastoma is the most frequent and aggressive brain cancer due to its ability to escape the immune system. However, the way in which this tumor manages to induce this immune tolerance was not known in detail. A research published in PNAS carried out a