New Treatments for AML Remain Elusive, But Researchers Are UndeterredLauren M. Green
A strength of Evolving treatment patterns and outcomes in older AML: changing everything to change nothing? is documenting the suspected increasing use of non-intensive induction therapy in persons age ≥60 years from 1% 1999 to 2006 to 23% from 2007, when azacytidine and decitabine became widely...
We also suggest strategies for trial design improvement. Although our focus is on the treatment of AML, the principles that we highlight should be broadly applicable to the evaluation of new treatments for a variety of diseases.doi:10.1038/s41375-018-0363-yEstey, Elihu...
When white blood cells that normally fight infection acquire mutations that cause them to multiply excessively, AML results. It is the most common acute leukemia in adults. Treatments for AML include chemotherapy, radiation, and medications that specifically target the protein drivers of A...
This is an exciting time for the AL amyloidosis community as patient advocacy groups, academia, pharmaceutical companies, and regulatory agencies are joining in an effort to develop safe and effective treatments for patients with AL amyloidosis. ...
This global educational program is intended for hematologists, medical oncologists, and other healthcare professionals who treat patients with MDS and AML. Learning Objectives Upon completion of this activity, participants should be able to:
although there has been progress along those lines. The other is treatments or approaches that will result in a tangible improvement in overall survival. With some of these drugs, there have been data to suggest at least a modest improvement in overall survival, but we would like to see with...
Ask your health care provider any questions you have about these or any other new treatments for your condition. Written By Digital Pharmacist Staff
These AML survival pathways are involved in drug resistance, evasion of the immune system, reprogramming metabolism, and impairing differentiation. In addition, based on the reports of enhanced clinical efficiencies when combining drugs or treatments, deeper investigation into possible pathways, which can...
Unfortunately, available Chokα inhibitors also have toxic side-effect and are not approved for use in patients. Hopefully, this research might encourage screening for safe drugs interfering with these pathways and contribute the development of new treatments for AITL....