It compares its efficacy as well as its health benefits to other medications for osteoporosis, including biophosphonates and estrogen treatment.Speroff, LeonOb/gyn Clinical AlertStrontium: a new treatment for ...
Denosumab: A New Treatment for Osteoporosis 来自 ProQuest 喜欢 0 阅读量: 23 作者: L Speroff 摘要: The article presents a commentary addressing a study on the effectiveness of denosaumab, a human monoclonal antibody, to treat osteoporosis in postmenopausal women. It is inferred that the ...
A recent study revealed that the permissive levels of butyrate produced by the GM are essential for iPTH to induce bone anabolism in mice.54In the absence of the GM, the anabolic effects of iPTH and antibiotic treatment resulted in no increase in Treg cells in the gut and BM. However, the...
A recent study revealed that the permissive levels of butyrate produced by the GM are essential for iPTH to induce bone anabolism in mice.54In the absence of the GM, the anabolic effects of iPTH and antibiotic treatment resulted in no increase in Treg cells in the gut and BM. However, the...
An international study by The University of Western Australia may lead to a new treatment for osteoporosis caused by age-related bone loss in elderly women. Osteoporosis is a common disease which makes bones become brittle and leads to a higher risk of breaks than in normal bone. It affects ...
Objectives:The aim of the study was to assess the effectiveness of postmenopausal osteoporosis treatment with natural sex hormones. Material and methods:The single-blind study included 210 women, randomly allocated to three different groups, with various methods of treatment: Group I (70 controls) re...
Denosumab is the international name of a human, monoclonal antibody approved for the treatment of osteoporosis. This antibody is associated with RANK ligand (RANKL), inactivating it. In consequence, the formation and survival of osteoclasts are suppressed, leading to their apoptosis. All this results...
Osteoporosis is a major public health concern, characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fracture. Fracture repair progresses through different pathways, striking a balance between bone formation and bone remodel...
Osteoporosis has become global health issue due to the longer life-cycle and increased percentage of older people in population. The great improvement was done in the treatment of postmenopausal osteoporosis. By the mechanism of action, drugs for osteoporosis treatment are antiresorptives and osteoanab...
"Clinically, we have very few ways to build bone, and all of those ways are associated with potential drawbacks," he said, "so having additional pathways that we can target to build new bone would open up new treatment models for not only osteoporosis, but other disorders of skeletal fragil...