What new treatments are on the horizon for osteoporosis? Ethel Siris, MD There are a number of new treatments on the horizon. They are somewhat farther a field, but there are, there's a drug that talks to the chemical that signals those bone eating cells, the osteoclasts, to block tha...
Reports on new treatments for osteoporosis. Agents widely used for treatment of the disease; Antiresponsive agents; Etidronate; Estrogen therapy; Bisphosphonates.SambrookPhilip N.KrucoffCarolSaturday Evening PostNew treatments for osteoporosis [editorial]. Lancet 1990; 335: 1065–6...
Osteoporosis continues to be an important field of biomedical research.doi:10.1007/s12020-011-9570-2G. MazziottiJ. BilezikianE. CanalisD. CocchiA. GiustinaSpringer USEndocrineG. Mazziotti, J. Bilezikian, E. Canalis, D. Cocchi, and A. Giustina. "New understanding and treatments for ...
New understanding and treatments for osteoporosisNew understanding and treatments for osteoporosisENDOCRINE - BASINGSTOKE-MazziottiG.BilezikianJ.CanalisE.CocchiD.GiustinaA.Mazziotti G, Bilezikian J, Canalis E, Cocchi D, Giustina A. New understanding and treatments for osteoporosis. Endocrine. 2012; 41...
This review will be a valuable reference for researchers and clinicians working on the development of new treatments for NCDs, specifically those targeting the Nrf2 pathway with natural compounds such as Que. 2. Crosstalk between oxidative stress, inflammation, and NCDs Inflammation and oxidative ...
With ever-increasing life expectancy comes the challenge of treating age-related disorders such as osteoporosis. Although there are effective drugs for treating this metabolic bone disease, they can be expensive and have side effects, limiting their avai
Denosumab is the international name of a human, monoclonal antibody approved for the treatment of osteoporosis. This antibody is associated with RANK ligand (RANKL), inactivating it. In consequence, the formation and survival of osteoclasts are suppressed, leading to their apoptosis. All this results...
To provide insights into these and related questions, we sought individual participant data on all recorded diabetes-related adverse events, treatments for diabetes, and measures of glycaemia recorded within the large, long-term, double-blind, randomised controlled trials of statin therapy that partic...
Mostajo D, Ñañez M, Ojeda E, Pilnik S, Rojas J, Salinas C, Sosa L, Spritzer PM, Tserotas K, Vallejo MS, Belardo A, Fighera TM, Chedraui P (2020) Metformin use is associated with a lower risk of osteoporosis in adult women independent of type 2 diabetes mellitus and obesity. ...
This review summarizes recent animal and human experimental data showing that pharmacological activation of SIRT1 may act in a manner that current treatments do not, namely by treating the imbalance in bone remodeling that is the root cause of osteoporosis and other bone disorders. Graphical abstract...