Abstract Although the incidence of hepatocellular carcinoma (HCC) is likely to start falling in many countries following mass vaccination programmes, large numbers of new cases are likely to be seen for many years to come. For the majority of patients, only palliative treatments can be offered. ...
The identification of such mechanisms may open new avenues for the prevention and treatment of HCC through the development of targeted therapies. In this review we will describe the new potential therapeutic targets and clinical developments that have emerged from progress in the knowledge of HCC ...
Many non-surgical treatments of hepatocellular carcinoma (HCC) have significantly improved in the last few decades and have shown survival benefits for selected patients withHCC. Today ablation can improve survival in individuals diagnosed in early HCC and even offer a curative treatment in selected ...
Curcumin-loaded galactosylated BSA nanoparticles as targeted drug delivery carriers inhibit hepatocellular carcinoma cell proliferation and migration. The main objective of this study was to develop novel BSA nanoparticles (BSA NPs) for improving the bioavailability of curcumin as an anticancer drug, and ...
New Drugs Effective in the Systemic Treatment of Hepatocellular CarcinomaWatch a video presentation of this article Watch the interview with the author Answer questions and earn CMEdoi:10.1002/cld.796John Wiley & Sons, LtdClinical Liver Disease...
Surgical therapy still remains the first-line treatment for end-stage HAE13,14. Brain metastasis is not a contraindication to surgery, and patients whose metastases were not located in important areas of the brain could still be treated with surgery. Previous treatments for HAE patients with IVC ...
This work was built on pre-clinical studies in animal models by Hala Elnakat Thomas, Ph.D., first author and research instructor in the department, who found that the combination of mTOR inhibitors were effective in the treatment of hepatocellular carcinoma (liver cancer) but had the potential...
Radiofrequency ablation and percutaneous ethanol injection treatment for recurrent local and distant well-differentiated thyroid carcinoma. Ann Surg. 2006;244(2... M Melany - Springer US 被引量: 0发表: 2012年 加载更多来源期刊 Radiology 研究点推荐 Subcentimeter Hepatocellular Carcinoma Percutaneous Radio...
In the latest issue of Molecular Therapy, Skoltech and MIT researchers have published a new combinatorial therapy for the treatment of liver cancer. Using a siRNA approach, a field in which Dr. Zatsepin (Skoltech) excels, coupled with lipid nanoparticle
Infection with the hepatitis B virus is one of the leading risk factors for developing hepatocellular carcinoma, particularly in East Asia1. Although surgical treatment may be effective in the early stages, the five-year overall rate of survival after developing this cancer is only 50–70%2. ...