Areas covered:We discuss recent data and ongoing research efforts to improve the treatment of hepatocellular carcinoma with discussion of current and upcoming systemic therapies combining agents of different classes. Expert opinion:Systemic therapy for HCC is in evolution. The inclusion of immunotherapy ...
Treatment protocols for hepatocellular carcinoma are provided below, including those for patients with unresectable disease and patients with special considerations. Treatment recommendations for patients with early-stage resectable disease For patients
Hepatocellular carcinoma (HCC) is a common type of tumor worldwide. The development of systemic treatment of advanced HCC has remained stagnant for a considerable period. During the last years, a series of new treatment regimens based on the combination of immunotherapeutic drugs and targeted drugs ...
First selective small molecule inhibitor of FGFR4 for the treatment of hepatocellular carcinomas with an activated FGFR4 signaling pathway. Cancer Discov. 5, 424–437 (2015). CAS PubMed Google Scholar Day, C.-P., Merlino, G. & Van Dyke, T. Preclinical mouse cancer models: a maze of ...
New Drugs Effective in the Systemic Treatment of Hepatocellular CarcinomaWatch a video presentation of this article Watch the interview with the author Answer questions and earn CMEdoi:10.1002/cld.796John Wiley & Sons, LtdClinical Liver Disease...
Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumors in the world. Therapeutic options for advanced HCC are limited. Systemic treatment, especially with conventional cytotoxic drugs, is usually ineffective. For more than a decade, sorafenib has been the only systemic...
Liver cancer, more specifically hepatocellular carcinoma (HCC), is the second leading cause of cancer-related death and its incidence is increasing globally. Around 50% of patients with HCC receive systemic therapies, traditionally sorafenib or lenvatini
Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumors in the world. Therapeutic options for advanced HCC are limited. Systemic treatment, especially with conventional cytotoxic drugs, is usually ineffective. For more than a decade, sorafenib has been the only systemic...
Treatment of hepatocellular carcinoma associated with cirrhosis in the era of liver transplantation. To review the treatment of cirrhotic patients with hepatocellular carcinoma in the era of liver transplantation and to determine the most appropriate appro... E Mor,R Turkaspa,P Sheiner,... - 《Ann...
Hepatocellular carcinoma (HCC) is a solid tumor that shows high heterogeneity of molecular phenotypes and is considered the second most common cause of cancer-related death. Studies show enormous potential for ADCs targeting GPC3 and CD24 and other tumor-associated antigens in HCC with their high,...