Results of the study by doctor M. M. B. Breteler and colleagues show that statins lower the number of new cases of the disease regardless of the type of statin used or the genetic risk for the disease of a person. Under the study, the subjects who use statins posed a 43% reduced ...
Still, studies conducted in younger individuals have not detected associations between leptin and early indicators of brain damage preceding late-life dementia risk. Researchers in the new study at UT Health San Antonio aimed to gain further insights into the potential relationships of leptin with neur...
In a study published today (January 21) inAlzheimer’s and Dementia: Translational Research & Clinical Interventions, Dr. Underwood, together with Dr. Ilianna Lourida from the University of Exeter, led a systematic review of existing scientific literature to look for evidence of prescription drugs ...
It modulates gamma secretase and is highly specific for its effects on Abeta -42 and, unlike the gamma secretase inhibitors, does not interfere with the function of Notch. In a phase II study, tarenflurbil was well tolerated for up to 24 months of treatment in 210 AD patients, with ...
This survey study examines rare disease expert perspectives on newborn genome sequencing and which gene-disease pairs they consider appropriate for
However, the populations participating in studies guiding FDA approvals are generally younger, more often male, and less racially and ethnically diverse, and they typically have fewer comorbid conditions than the CMS beneficiary population. Study inclusion and exclusion criteria may demonstrate th...
VPN also effectively manages epilepsy and dementia through the modulation of synaptic plasticity and neurotransmission (Meador et al. 2021). A recent randomized clinical trial by Garza-Morales et al. (2019) showed that VPN effectively treated focal epi- lepsy. An experimental study confirmed ...
It is noteworthy that oral hypoglyce- mic agents might have protective effects against other neuropsychiatric disorders, including dementia and Par- kinson's disease [8,9], suggesting that these agents could have effects on pathways to neuroprogression that may be overlapping in these disorders. ...
In this context, another study stated that treatment with protease-resistant, a cyclic form of Ang (1–7) (cAng 1–7), could restore the ACE-2 activity; attenuated the inflammatory response; decreased lung injury and improved lung function [124], [127]. That confirms the positive ...
“In just minutes, our algorithm solves a challenge that would take researchers several weeks. That it will now be easier to study microscopic images of clumping proteins will hopefully contribute to our knowledge, and in the long term, lead to new therapies for neurodegenerative ...