Multiple studies have revealed SJL mice as a valid model for malignant lymphoproliferative tumors. In these mice the germinal center (GC) B cells express the vSAg superantigen of a mammary tumor virus (mtv-29), which is known for its capacity to stimulate CD4+T cells, which will in turn ...
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Pauline Soo has more than 20 years’ experience in healthcare and aged care. In her role as Datacom’s Health Director, she is focused on helping tackle sector-wide challenges –including scarce resources and heavy regulatory and compliance requirements – with innovative thinking and smart tech....
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However, it has been noted that colon-cancer MC38 cells used in the aforementioned experiment can be used as a model for hypermutated/microsatellite-unstable tumors [89]. These results may have been affected by neoantigen-mediated immune activation. In addition to hormones, the type of genetic ...
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Overall, the indices suggested that the effect size for the association between the GRS and AD was small but significant. Despite this modest effect, the inclusion of the GRS into the predictive model consistently improved the assignment of the risk of progression, as expressed by the net ...
Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) has gained widespread use in practice for its simplicity and non-invasive nature. However, its ability to quantify insulin resistance values becomes limited when the pancreatic beta-cell function is impaired or depleted, making it more ...
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As senior vice president, federal policy, Cristina Freyre Batt oversees all of the Healthcare Association of New York State’s federal government relations and advocacy activity. Batt works with federal policymakers and HANYS members to advance the association’s legislative and regula...