With respect to treatment of symptomatic neuropathy, parenteral administration of the antioxidant alpha-lipoic acid has been shown to relieve neuropathic pain, whereas topical application of clonidine or capsaicin may benefit some patients. Further evidence that long-term administration of a number of ...
Diabetic Neuropathy: New Recommendations for Primary Care Diabetic neuropathies are the most prevalent chronic complications of diabetes—and they are often devastating for the patient. Estimates of the incidence and prevalence of diabetic neuropathies vary greatly, but several large observational cohorts and...
New perspective on diabetic neuropathy pathogenesis and treatmentInpharma Weekly -doi:10.2165/00128413-199409320-00003NoneSpringer International PublishingInpharma Weekly
The pathogenesis of diabetic neuropathy remains unclear but is thought to involve various mechanisms. This complication can be traced to the metabolic effects of hyperglycemia and/or other effects of insulin deficiency on the various constituents of the peripheral nerve. The polyol pathway and/or ...
Painful diabetic neuropathy seriously affects quality of life (QOL) and the ability to function.1 However, this condition is often unre-ported and more often untreated, with an estimated two out of five cases not receiving care.2 In addition, community-based data suggest that the use and dos...
TE Fox,M Kester - 《Advances in Experimental Medicine & Biology》 被引量: 54发表: 2010年 Auditory neuropathy in streptozotocin-induced diabetic mouse An investigation of the mechanism of damage to the peripheral nervous system and central nervous system in diabetes mellitus (DM) is highly important...
The present review was supported by the National Natural Science Foundation of China (81873076), the Shanghai Talents Development Fund Project (2017090) and the Hundred Talents Program from Shanghai University of Traditional Chinese Medicine. Ethics approval and consent to participate Not applicable. Co...
diabetic mice, leading to the conclusion that sensory neuropathy is related to this decline in the dendritic cell population in the diabetic cornea. Furthermore, dendritic cells were found to guide the regenerating corneal sensory nerve fibers after wounding; this association is disrupted in the ...
Pediatric neuropathy attributed to metabolic dysfunction is a well锕宯own complication in children and youth with type 1 diabetes. Moreover, the rise of obesity and in particular of type 2 diabetes may cause an uptick in pediatric neuropathy incidence. However, despite the anticipated increase in ...
The 9th Cardiovascular Outcome Trial (CVOT) Summit: Congress on Cardiovascular, Kidney, and Metabolic Outcomes was held virtually on November 30-December 1, 2023. This reference congress served as a platform for in-depth discussions and exchange on recen