Evaluation of DA- 9801, a new herbal drug for diabetic neuropathy, on metabolism-mediated interaction [ J ]. Arch Pharm Res, 2013,36(1) :1-5.Ji HY,Liu KH,Kong TY,et al.Evaluatioin of DA-9801,a new herbal drug for diabetic neuropathy,on metabolism-mediated interaction[J].Arch Pharm ...
“We are honored to work with Lexicon to advance this novel therapy for diabetic peripheral neuropathy with the potential to positively impact the lives of patients suffering from this condition.” According to the Mayo Clinic, diabetic neuropathy is ...
ArticleDeriving Schwann cells from hPSCs enables diseasemodeling and drug discovery for diabetic peripheralneuropathyGraphical abstractHighlightsd Differentiation of hPSCs yields authentic myelinatingSchwann cellsd Schwann cells are selectively vulnerable to glucotoxicityd Drug screen identif i es candidates that...
Evaluation of DA-9801, a new herbal drug for diabetic neuropathy, on metabolism-mediated interaction. Arch. Pharm. Res. 36, 1–5 (2013). PubMed Google Scholar Roemer, T. & Krysan, D. J. Antifungal drug development: challenges, unmet clinical needs, and new approaches. Cold Spring Harb...
we could also predict novel pathways whose roles in DN remain to be confirmed in future studies. NGF signaling pathway which is related to diabetic neuropathy was amongst the enriched pathways110. Similarly, the platelet degranulation pathway was detected as a potential role player in DN. Previous...
Diabetic Peripheral Neuropathy Multiple Sclerosis Parkinson’s Disease Others Acute and Chronic Pain Inflammatory / soft tissue injuries Low back pain Migraine pain Neuropathic pain Rheumatoid and osteoarthritis pain Psychiatry Depressive disorders Biopolar disorder ...
5 Duloxetine Depression, Diabetic Neuropathies Urinary incontinence, fibromyalgia, musculoskeletal pain, shoulder pain, back pain, osteoarthritis, Diabetic peripheral neuropathy [30,31] 6 Chlorpromazine Anti-emetic, antihistamine Non-sedating tranquillizer [32] 7 Galantamine Polio, paralysis and anaesthesia ...
Pain models (CINP: Chemotherapy-induced neuropathic pain; PDN: painful diabetic neuropathy; PNL: partial nerve ligation; SNI: spared nerve injury). 7. Concluding Remarks Tetrodotoxin has been evaluated for the relief of pain as a consequence of neuropathies or cancer, both at the preclinical and ...
糖尿病是一种以高血糖为特征的代谢性疾病,糖尿病周围神经病变(Diabetic Peripheral Neuropathy, DPN)则是糖尿病最常见的慢性并发症之一。DPN的特征是周围神经从远端到近端逐渐退化,从而导致感觉症状的异常,包括疼痛、虚弱和/或感觉丧失。建立合适的体内研究模型对于研究DPN病理机制和开发新的治疗策略至关重要。· ...
When symptoms of peripheral neuropathy appear, the possibility that they have been induced by drugs should be considered. A large number of drugs of all ki