It is essential to investigate the potential synergy between a new drug and existing medications approved by the US FDA. This approach could even be extended to situations where adjuvant treatment, such as tau-related treatments, is provided after amyloid clearance has been achieved. Clinical trials...
Bisphosphonates are the most commonly used medications in the treatment of postmenopausal osteoporosis. Denosumab, a new approach to fracture prevention, is a fully human monoclonal antibody that targets nuclear factor-κB ligand (RANKL), an important cytokine regulating formation and function of ...
New and Emerging Biological Medications for Asthma, Allergic Rhinitis and Chronic Rhinosinusitis: a Concise ReviewBiologicsAllergic rhinitisChronic rhinosinusitisAsthmaThe purpose of the study is to survey the current literature describing the use of biologic agents in the treatment of asthma, allergic ...
30,31 Similarly, using scheduled nonnarcotic medications, such as acetaminophen and ketorolac or ibuprofen, has been shown to reduce the total OME requirement per patient.27,28 Enhanced Recovery After Surgery protocols for obstetrics have the potential to coordinate pain management across the delivery ...
Cancer is the world's second-leading cause of death. Drug development efforts frequently focus on medicinal plants since they are a valuable source of anticancer medications. A phytochemical investigation of the edible Ziziphus spina-christi (F. Rhamnace
combined with subsequent optimization of leads through modern medicinal chemistry, followed by toxicology and metabolic studies and an understanding of basic pharmacokinetics, would lead to a range of new and more effective medications for those who did not respond well to the original antipsychotics, ...
specialized pharmacological and surgical treatment interventions are recommended. With this staging system, once patients reach stage C or D and have symptoms, they cannot revert to stage A or B, indicating that although symptoms may be controlled with medications the disease is continuing to progress...
Even though new drugs will help to improve the prognosis of people with DKD, it becomes more and more a challenge for physicians to choose the most beneficial medication or combination of medications for an individual patient. There is a need to evaluate the kidney-protective effects of ...
High-Sensitivity Cardiac Troponin for the Diagnosis of Patients with Acute Coronary Syndromes Article 24 August 2017 Notes 1. Single-channel SQUID device could, in principle, be compared to a single V-lead ECG system. 2. The Siemens KRENIKON 37-channel; the Philips 62-channel featuring a Twi...
intranasally administered CGRP receptor antagonist that is approved for the acute, but not for the prophylactic treatment, of migraine (Dhillon2023c; Larik et al.2023). Intranasal zavegepant may benefit patients with migraine for whom oral medications are ineffective, slow-acting, or intolerable due...