Using laboratory-grown roundworms as well as human and mouse eye tissue,University of Maryland School of Medicine(UMSOM) researchers have identified a new potential mechanism for age-related macular degeneration — the leading cause of blindness among older adults. The UMSOM researchers say that the...
Eter N., Krohne T.U., Holy F.: New Pharmacologic appro- aches to therapy for age-related macular degeneration. Bio- drugs 2006;20(3):168-79.Eter N, Krohne TU, Holz FG. New pharmacologic approaches to therapy for age-related macular degeneration. Biodrugs 2006; 20 (3): 167–79 View...
Medical College of Georgia scientists report that a gene previously implicated in the development of atherosclerotic lesions in coronary arteries could be key to understanding why many people don't benefit from the most used therapy for neovascular age-related macular degeneration (AMD), a leading cau...
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therapy is specifically intended for use in children with a confirmed DMD gene mutation, who can still walk, and is administered as a single-dose intravenous infusion. Results from clinical studies have confirmed the achievement of dystrophin expression with delandistrogene therapy, leading to ...
R J Yáñez-Muñoz - 《Gene Therapy》 被引量: 1发表: 2017年 Cell Therapy for Age-Related Macular Degeneration: A New Vision for the Bone Marrow? In this issue of Molecular Therapy, Qi et al.1 report that a cell therapy can improve retinal structure and vision in a mouse model of ...
The AMD Gene Consortium Nature Genetics45,433–439 (2013)Cite this article 19kAccesses 97Altmetric Metrics Abstract Age-related macular degeneration (AMD) is a common cause of blindness in older individuals. To accelerate the understanding of AMD biology and help design new therapies, we executed ...
with a passion for biologics mass spectrometry and gene therapy. Within QPS, he is an integral part of the preclinical and bioanalysis team supporting a first in the industry – the world’s largest gene therapy trial with patients numbering more than a million. Lam is a regularly published...
"This work has future implications to enhance outcomes of RPE cell therapy. For example, prior to transplantation, RPE cells in culture that display this distinct gene expression profile can be selectively chosen for RPE transplant to enhance post-transplant survival. Moving forward, we hope to dev...
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the developed western world, accounting for approximately 50% of all cases of registered blindness. The rising prevalence of this disease in Asia seems to parallel the same trend in the developed world. Because...