Insufficient patient enrollment per month (=accrual) is the leading cause of cancer trial termination. To identify and quantify factors associated with pat
Investigational New Drugs Novel Anti-Cancer Therapeutics and Therapies Publishing model: Hybrid Submit your manuscript Explore open access fundingSelect institution Overview Investigational New Drugsis a forum for rapid dissemination of information on new anticancer agents. ...
In 2023 and 2024, 30 and 43 new drugs were authorized by the EMA, respectively, and consequently marketed in Germany (and also other EU countries) [13–14]. A closer look at the profile of the 73 newly introduced agents [15–16] showed that 18 of them can be categorized as having mu...
the PROTAC degrades the protein continuously. It is also far more potent and can be used to treat more-severe diseases. Most of the PROTAC drugs currently in clinical trials target some form of cancer, but in the
Colorectal cancer or colon cancer is cancer of the large intestine (colon), which is the final part of the digestive tract. Both colon cancer and rectal cancer can be referred to as colorectal or bow
Cancer patients are not the only ones negatively impacted by these actions. In 2023, the MAC Palmetto GBA, published an article to the CMS website, changing the coverage of two tests for organ transplant patients --one of which could predict rejection problems with transplanted organs weeks or...
Foreseeing the devastating impact of the New Drugs, Cosmetics & Medical Devices Bill, 2023 on the domestic players and India’s preparedness to deal with any pandemic like situation, multiple stakeholders have joined hands and want the New Drugs, Cosmetics & Medical ...
Chauhan J, et al.Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4.Nat Commun. 2023;14(1):2192. Published 2023 Apr 25. doi: 10.1038/s41467-023-37811-3.
Article Open access 09 January 2023 EXOSC8 promotes colorectal cancer tumorigenesis via regulating ribosome biogenesis-related processes Article 08 November 2022 Change history 25 January 2018 In this article a source of grant funding for one of the authors was omitted from the Acknowledgements sec...
anti-cancer drugs stimulated and encouraged the production of biofilms [239,292]. An inducible DNA damage repair pathway known as the SOS response is activated by the bacteria growing on the cancer cells to evade the drug onslaught [293]. As a result, several distinct bacterial phenotypes emerge...