Infection.This is the most common cause of a high neutrophil count. Most bacterial infections cause a high neutrophil count, but not all of them do. Viral infections don't generally cause neutrophilia, but they may in the early stage of infection. Some fungal and parasitic infections can cause...
role of neutrophil death in homeostasis has not been resolved. The situation in infection/inflammation is drastically different, as local massive cell death of neutrophils can be observed under these conditions. The green aspect of pus is caused by the liberation of (green) myeloperoxidase from dyin...
Fig. 1: Pre-exposure to LPS protects mice from a lethal infection by PA14 with reduced bacterial burden and a regulated inflammatory response. a Schematic of PA14 infection with or without LPS pre-treatment. Bacterial load showing reduced bacterial burden in the lung (b) and decreased periphera...
The view of neutrophils has shifted from simple phagocytic cells, whose main function is to kill pathogens, to very complex cells that are also involved in immune regulation and tissue repair. These cells are essential for maintaining and regaining tissu
BAL neutrophils, serum procalcitonin, and C-reactive protein to predict bacterial infection in the immunocompromised host. Chest. 2007;132:504-14.Stolz D, Stulz A, Muller B, et al. BAL neutrophils, serum procalcitonin, and C-reactive protein to pre- dict bacterial infection in the ...
Initial attachment of neutrophils to endothelial cells is determined by the endothelial cells, which react to stimuli such as TNFα, IL-1β, and IL-17 that are generated during infection or inflammation. Such stimulation results in expression of P-selectin (also expressed by activated platelets),...
Bacterial infectionNoise-induced extinctionWe study stochastic phenomena for a model of bacterial infection and neutrophils defense. Sufficient conditions of stochastic permanence and extinction for the random model are discussed. To explore the effect of different noises on the bacteria dynamics, we ...
A Functional Role of Neutrophils in the Regulation of Innate and Acquired Immunity to Bacterial InfectionNewtrophilstoll-like receptorchemokinescross-presentationNeutrophils express receptors that specifically recognized microorganisms and viruses and efficiently ingest and destroy these pathogens. Moreover, ...
Non-tuberculous Mycobacterial Pulmonary Disease (NTM-PD) is an increasingly recognised global health issue. Studies have suggested that neutrophils may play an important role in controlling NTM infection and contribute to protective immune responses with
Evidence for means of mobilization of calcium (and in particular calcium influx) in human neutrophils other than through SOCE has also been obtained. For example, whereas engagement of CD32a leads to a rapid and robust mobilization of calcium in human neutrophils, this is not accompanied by a ...