Regulated production of the interferon‐γ‐inducible protein−10 (IP‐10) chemokine by human neutrophils Interferon-γ (IFN-γ)-inducible protein-10 (IP-10), a member of the C-X-C sub-family of chemokines, is known to be produced by monocytes, lymphocytes, ker... MA Cassatella,S ...
In addition to neutrophil interactions with B cells, myeloid-derived suppressor cells (MDSCs), which are a neutrophil population (see neutrophil heterogeneity in chronic inflammation), can regulate T cells in chronic inflammatory conditions. Thus, skin from psoriatic patients accumulates more MDSCs than...
Neutrophils, the most abundant cell type in the blood in humans, are a fundamental component of the innate immune response. It is estimated that each day 1 billion neutrophils are produced per kilogram of body weight and that this can increase to 10 billion during an infection.1At steady stat...
(C–E) Energy status measurement (ATP/ADP) of neutrophils cultured for 2 h in the presence and absence of pathway inhibitors 10 mM 2-DG (C; n = 4), 1.2 μM oligomycin A (D; n = 3), and 10 μM etomoxir (E; n = 3). (F and G) Energy charge measurement ([ATP + 1/2ADP...
Activated neutrophils (ANs) are known to release reactive oxygen species that may cause oxidative damage to surrounding tissues. We determined if ANs could induce lipid peroxidation (LP) in human red cells and investigated the mechanism involved in this interaction. We studied neonatal glucose-6-...
Mature CD10(+) and immature CD10(-) neutrophils present in G-CSF-treated donors display opposite effects on T cells (vol 129, pg 1343, 2017) Marini,O.,Costa,... - 《Blood the Journal of the American Society of Hematology》 被引量: 13发表: 2017年 Mature CD10(+) and immature CD10...
上海玉博生物科技有限公司做为AROTEC Diagnostics代理商之产品ATM01-10-Myeloperoxidase (pANCA) ATM01 Native - Human Neutrophils的产品销售公司,专业经营原装进口抗体(单克隆、多克隆)、重组蛋白、检测试剂盒、标准品、细胞因子、胎牛血清、细胞培养类等生物试剂以及耗材。 ATCC sigma anatrace caroteNature NIBSC med...
Unlike other cell types in the body, the nuclei of granulocytes, particularly neutrophils, are heavily segmented into multiple lobes. Although this distinct morphological feature has long been observed, the underlying mechanism remains incompletely characterized. In this study, we utilize cryo-electron ...
Neutrophils were unique among leukocytes in responding to CFP-10, as monocytes and lymphocytes failed to produce a Ca(2+) signal upon stimulation with the M. tuberculosis protein. Hence, CFP-10 may contribute specifically to neutrophil recruitment and activation during M. tuberculosis infection, ...
Neutrophils are myeloid cells that constitute 50–70 % of all white blood cells in the human circulation. Traditionally, neutrophils are viewed as the first line of defense against infections and as a major component of the inflammatory process. In addition, accumulating evidence suggest that neutrop...