胞外杀菌网络,通常简称为NETs(Neutrophil Extracellular Traps),是中性粒细胞在面对病原体时释放的一种网状结构。这种结构由DNA、组蛋白和抗菌蛋白组成,可以捕捉和杀灭病原体,从而限制感染的扩散。注:《詹韦免疫生物学》9th中文版将Neutrophil Extracellular Traps翻译为“中性粒细胞胞外杀菌网络”,p639名词解释 在扫描...
References 17 and 18 uncover a role for MPO and NE in promoting chromatin decondensation and a potential link with susceptibility to fungal infection in MPO-deficient individuals. CAS PubMed PubMed Central Google Scholar Schauer, C. et al. Aggregated neutrophil extracellular traps limit ...
The role of the MPO-NE pathway is supported by studies of neutrophils from diabetes patients with hereditary MPO deficiency at high risk of infection.145Bellaaouaj et al. have reported that mice with NE deficiency are more susceptible to sepsis and death,146and NE inhibition prevents NET formati...
Neutrophil extracellular traps (NETs) are structures composed of DNA, histones, and antimicrobial proteins that are released extracellularly by neutrophils and other immune cells as a means for trapping and killing invading pathogens. Here, we describe NET formation in milk and in mammary alveoli of...
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Neutrophil extracellular traps (NETs) — formation and :中性粒细胞外的陷阱(网)的形成和粒细胞,traps,NETs,and,NETs的,trap,Traps,中性粒细胞 文档格式: .pdf 文档大小: 2.95M 文档页数: 8页 顶/踩数: 0/0 收藏人数: 3 评论次数: 0 文档热度: ...
During the process of NETosis, neutrophil extracellular traps (NETs) that contain large web-like structures of decondensed chromatin decorated with histones and intracellular components, including neutrophil elastase (NE), myeloperoxidase (MPO), high mobility group protein B1 (HMGB1), and proteinase 3...
半滑舌鳎(Cynoglossus semilaevis)中性粒细胞胞外陷阱(neutrophil extracellular traps):产生特征以及抗菌作用 中性粒细胞胞外陷阱(NETs)是中性粒细胞释放到胞外的网状纤维结构,它作为机体一种细胞免疫防御机制抵抗了微生物的入侵。NETs是以DNA作为基本结构骨架,其上间隙附着大量的蛋白结构。 NETs的产生被称作“NETosis”...
et al. Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease. Nat Med 22, 146–153 (2016). https://doi.org/10.1038/nm.4027 Download citation Received01 September 2015 Accepted09 December 2015 Published18 January 2016 Issue ...
Neutrophils perform critical functions in the innate response to infection, including through the production of neutrophil extracellular traps (NETs) - web-like DNA structures which are extruded from neutrophils upon activation. Elevated levels of NETs h