Neuropeptide-like proteinNLPNematodeParasiteNematode parasite infections cause disease in humans and animals and threaten global food security by reducing productivity in livestock and crop farming. The escalation of anthelmintic resistance in economically important nematode parasites underscores the need for ...
Urotensin II is the endogenous ligand of a G protein-coupled orphan receptor, SENR (GPR14). Biochem Biophys. Res. Commun. 265, 123-129 identified as the endogenous ligands of a G-protein-coupled orphan receptor, SENR (sensory epithelium neuropeptide-like receptor), which is identical to .....
In order to extend our knowledge on the occurrence of neuropeptide Y (NPY)-like-immunoreactive cells in the vitellointestinal duct and yolk sac of oviparou... Chiba,Akira,Honma,... - 《Zoological Science》 被引量: 3发表: 1995年 The unfolded protein response is activated in Alzheimer's dis...
The pleiotropic functions of NPY in humans are mediated by G protein-coupled receptors (Y1R, Y2R, Y5R), which activate several signaling pathways and thereby regulate cell growth, differentiation, apoptosis, proliferation, angiogenesis, and metabolism. These activities of NPY are highly relevant to...
Other neuropeptides, like proctolin, LK, TK, and FMRF-related peptides that had been isolated based on their myotropic activity, were employed extensively in tests of activity on different visceral muscle (Holman et al.1991,1990; Schoofs et al.1993). First of all, monitoring peptide actions...
Neurons have a central role in the systemic coordination of mitochondrial unfolded protein response (UPRmt) and the cell non-autonomous modulation of longevity. However, the mechanism by which the nervous system senses mitochondrial stress and communicat
Orphanin FQ: A neuropeptide that activates an opioidlike G protein-coupled receptor. 喜欢 0 阅读量: 45 作者:Reinscheid,Rainer K.,Nothacker,Hans-Peter 摘要: Features a research study on the nature and functions of the neuropeptide orphanin FQ. Materials and methods used; Comparison of the ...
The receptor protein that is activated by NPY is a metabotropic G-protein coupled receptor in the rhodopsin-like GPCR family coupling to Gi, thereby inhibiting adenylate cyclase. The Y-receptor proteins contain seven membrane spanning domains and all have been identified in human and rodents, ...
Adenosine, like some neuropeptides, has been classified as an ‘endogenous anticonvulsant’ (Dragunow and Goddard, 1984), given its apparent ability to suppress seizure activity in the brain. Patients experiencing seizures have strong upregulation of dialysate adenosine levels at seizure foci, and this...
The present invention relates to polynucleotide and polypeptide molecules for zpep17, a novel secreted protein. The polynucleotides encoding zpep17, may, for example, be used to identify a region of the genome associated with human disease states. The present invention also includes methods for pr...