Reagents which regulate human neuropeptide Y-like G protein-coupled receptor (NPY-like GPCR) protein and reagents which bind to human NPY-like GPCR gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, obesity, diabetes, ...
The present invention relates to polynucleotide and polypeptide molecules for zpep17, a novel secreted protein. The polynucleotides encoding zpep17, may, for example, be used to identify a region of the genome associated with human disease states. The present invention also includes methods for pr...
Neuromodulation enables transient restructuring of anatomically fixed neural circuits, generating alternate outputs and distinct states that allow for flexible organismal responses to changing conditions. We recently identified a requirement for the neuropeptide-like protein NLP-12, a Caenorhabditis elegans homol...
Analysis of the adaptor protein profile of the material eluting from the Sephacryl S-1000 column demonstrates a wide distribution of the Golgi-associated AP-1 (HA-I) molecules (AP47 and AP19) in relation to the CCV peak, spanning both the ascending and descending portions of the CCV peak...
Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor Neuropeptide Y--a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide. Neuropeptide Y (NPY)-like immunoreactivity in peripheral noradrenergic neurons and effects of NPY on sympathetic...
Calcitonin receptor-like (CALCRL) is a G-protein-coupled neuropeptide receptor involved in the regulation of blood pressure, angiogenesis, cell proliferation, and apoptosis, and is currently emerging as a novel target for the treatment of migraine. This study characterizes the role of CALCRL in ...
In order to extend our knowledge on the occurrence of neuropeptide Y (NPY)-like-immunoreactive cells in the vitellointestinal duct and yolk sac of oviparou... Chiba,Akira,Honma,... - 《Zoological Science》 被引量: 3发表: 1995年 The unfolded protein response is activated in Alzheimer's dis...
Orphanin FQ: A neuropeptide that activates an opioidlike G protein-coupled receptor. 喜欢 0 阅读量: 45 作者:Reinscheid,Rainer K.,Nothacker,Hans-Peter 摘要: Features a research study on the nature and functions of the neuropeptide orphanin FQ. Materials and methods used; Comparison of the ...
Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response. Genetics 2006; 174:229-239. 5 Yoneda T, Benedetti C, Urano F, Clark SG, Harding HP, Ron D. Compartment-specific perturbation of protein handling SPRINGER NATURE | Cell Research ...
The receptor protein that is activated by NPY is a metabotropic G-protein coupled receptor in the rhodopsin-like GPCR family coupling to Gi, thereby inhibiting adenylate cyclase. The Y-receptor proteins contain seven membrane spanning domains and all have been identified in human and rodents, ...