pro-survival signaling does converge on some common core components (Figure 2). However, data accumulated over the recent years show that different types of neurons in the brain might use different pro-survival mechanisms as there are a
These results indicate that focal alteration of cortical functions can initiate spreading of dysfunction along neuronal pathways in the brain, reminiscent of diaschisis-like processes.Similar content being viewed by others Microglia contribute to neuronal synchrony despite endogenous ATP-related phenotypic ...
Focuses on a study which developed noninvasive neuronal fiber tracking for use in living humans, using the ability of magnetic resonance imaging to characterize water diffusion. How the study was conducted; Results; Discussion of the results.Conturo...
L Faff-Michalak,J Albrecht - 《Metabolic Brain Disease》 被引量: 125发表: 1991年 Modulation of neuronal function by intracellular pH. Recent studies have revealed that excitation of specific nerve pathways can produce localized changes of pH in nervous tissue. It is important to determine... KI...
The brain ISS has been hypothesized to be highly connected so that at any given location in the brain extracellular space, molecules such as water could travel through multiple pathways to reach another location10. However, we did not observe such a global connectivity in this study. Rather, ...
In addition to being a putative third (or fourth) messenger involved in of signals to the genetic material, activation of IEGs has proven to be a useful tool for the study of transsynaptic activation of certain neuronal pathways in the brain. Thus, studies on the induction of IEGs are ...
Connections between neurons can be mapped by acquiring and analysing electron microscopic brain images. In recent years, this approach has been applied to chunks of brains to reconstruct local connectivity maps that are highly informative1–6, but nevert
Neuronal activity controls the strength of excitatory synapses by mechanisms that include changes in the postsynaptic responses mediated by AMPA receptors. These receptors account for most fast responses at excitatory synapses of the CNS, and their activity is regulated by various signaling pathways which...
The tuberomammillary nucleus (TMN) of the posterior hypothalamus, which contains the sole source of neuronal HA in the brain, is reciprocally connected to... KA Michelsen,L Adrian,K Jan,... 被引量: 0发表: 2014年 Tracing Central Pathways with the Autoradiographic Method1,2 A study of retr...
As a major neuron type in the brain, the excitatory neuron (EN) regulates the lifespan in C. elegans. How the EN acquires senescence, however, is unknown. Here, we show that growth differentiation factor 11 (GDF11) is predominantly expressed in the EN in the adult mouse, marmoset and hu...