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Compounds with asymmetric centers give rise to enantiomers (optical isomers), diastereomers (configurational isomers) or both, and it is intended that all of the possible enantiomers and diastereomers in mixtures and as pure or partially purified compounds are included within the scope of this ...
Dendritic GOPs likely serve as local secretory stations94,193 and/or non-centrosomal MT organization centers.78 Both in vitro and in vivo observations showed that GOPs could directly nucleate and orientate dendritic MTs to regulate dendrite development.78,83 However, an independent study did not supp...
When CA is intact, a negative or near-zero correlation is expected as cerebral neuroprotective mechanisms work to maintain constant CBF irrespective of any shift in MAP. As CA is impaired, CBF and MAP become more positively correlated and CA indices trend toward 1. The low and high values of...
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Making comparisons between cohorts of HUS patients treated using different protocols in different centers is not optimal. Differences in the case definition, case capture, inclusion of aHUS patients, length of follow-up, and treatment modalities, along with demographic variables and the genetic backgrou...
Physiologic dysregulation of the medullary respiratory rhythm generator, which has afferent inputs from the pons, mesencephalon, and higher cortical centers. A recent trial of patients with severe brain injury monitored for brain tissue oxygen showed brain tissue hypoxia worsened when EtCO2values were ...
Partnering urban academic medical centers and rural primary care clinicians to provide complex chronic disease care. Health Aff. 30, 1176–1184 (2011). Article Google Scholar Arora, S. et al. Demonopolizing medical knowledge. Acad. Med. 89, 30–32 (2014). Article PubMed Google Scholar [...
Anxiety-related events, like feeling of syncope and/or dizziness, are particularly common. For example, Centers for Disease Control and Prevention, in a report published on April 30, 2021, recorded 64 anxiety-related events (syncope in 17) among 8,624 Janssen COVID-19 vaccine recipients. None...
with a neurological syndrome before the tumor is identified [69,70,73]. Most patients (68–75%) with Ma2-IgG were men, with a median age of 60 years, although men may present at a younger median age of 34 years, while the median age for women may be older near 64 years [69,70...