Exosomes are essential paracrine mediators, which can participate in cell communication through substance transmission. In this regard, this review mainly discusses the current research progress of neural stem cell-derived exosomes. This paper mainly introduces the self-regulation of neural stem cells (...
近日,来自南方医科大学中西医结合医院神经外科的陈陆馗教授等学者在BIOCELL期刊发表了题为“Neural stem cell-derived exosomes: a cell-free transplant for potential cure of neurological diseases”的综述文章,收录于特刊 Exosomes in Cell Communication and Disease: From Biomarkers to Therapeutic Targets中。文章主要...
1. Neural stem cell-derived exosomes: a cell-free transplant for potential cure of neurological diseases 神经干细胞来源的外泌体:一种用于神经系统疾病潜在治疗的无细胞移植方法 JIAJUN HUANG, WEI WANG, WENTONG LIN, HENGSEN CAI, ZHIHAN ZHU, WAQAS AHMED, QIANKUN ZHANG, JIALE LIU, YIFAN ZHANG, RONG...
The exosomes were shown to contain T-cell immunoglobulin mucin protein 4 (TIM-4), which binds phosphatidylserine. Treatment with anti-TIM-4 antibody significantly blocked the exosome-mediated Ad5 entry. Conclusion: Neural stem cell-derived exosomes mediated significant cellular entry of Ad5 in a ...
We investigated the effects of unconditioned neural stem cell derived exosomes as post-injury treatment for cardiomyoblasts from three neuronal culture conditions; adherent cultures, neurosphere cultures and bioreactor cultures. Small extracellular vesicles were enriched with serial ultracentrifugation, validated...
exosomesischemic strokeneural progenitor cellsVascular endothelial cells were activated during acute ischemic brain injury, which could induce neural progenitor cell proliferation and migration. However, the mechanism was still unknown. In the current study, we explored whether vascular endothelial cells ...
stem cell-derived exosomes (BMSC-EXOs) can be substituted for BMSCs in cell transplantation. However, the underlying mechanisms remain unclear. In this study, a rat model of T10 spinal cord injury was established using ...
Collectively, these findings confirm that exosomes derived from neural stem cells undergoing necroptosis play an important role in cellular communication after spinal cord injury and induce TSC2 upregulation in recipient cells. 展开 关键词: cellular communication competing endogenous RNA exosomes Foxp1 ...
Abstract P751: Global Analyses of Protein and Microrna Cargo in Neural Stem Cell Derived-Exosomes After Brain Ischemia Background: Adult neurogenesis facilitates brain remodeling after stroke. Exosomes derived from neural stem cells (NSCs) promote ischemic neurovascular rem... XS Liu,B Fan,C Li,....
38 Intranasal administration of stem cell-derived exosomes for central nervous system diseases 干细胞来源的外泌体鼻腔给药治疗中枢神经系统疾病 Shuho Gotoh, Masahito Kawabori, Miki Fujimura Neural Regeneration Research Jun-24 获取全文: 39 Understanding the spectrum of non-motor symptoms in multiple sclero...