Therefore, NeuN has been considered to be a reliable marker of mature neurons for the past two decades. However, this role has been challenged by recent studies indicating that NeuN staining is variable and even absent during certain diseases and specific physiological states. More importantly, ...
We report here immunocytochemical studies of NeuN protein expression in neurons in the substantia nigra (SN) of the human brain ( n = 14, age 27–78 years). Weak positive reactions for NeuN protein were seen in some SN neurons, while other neurons were negative. Overall, reactions for NeuN...
Furthermore, the co-localization of BrdU with NeuN in the dentate gyrus in vivo confirmed that the proliferating cells differentiate into neurons [133]. Recently a shorter VGF peptide, TLQP-21, was shown to prevent cerebellar granule cell death induced by serum and potassium deprivation in a ...
NeuN (Neuronal Nuclei) is a neuron-specific nuclear protein that has recently been identified as Fox-3/Rbfox3, a member of the Fox-1 family of transcription factors.NeuN is only expressed in the nuclei of differentiated neurons. In some neurons - Purkinje cells, sympathetic ganglion cells, ...
some neurons fail to be recognized by NeuN at all ages: INL retinal cells, Cajal-Retzius cells, Purkinje cells, inferior olivary and dentate nucleus neurons, and sympathetic ganglion cells are examples. Immunohistochemically detectable NeuN protein first appears at developmen...
Normally, the immune response of the antibody is transiently observed only in the mitotic period of neuronal cells, whereas NeuN is not expressed during cell proliferation. NeuN is a very good reference, expressed in mature neurons and retinoic acid-stimulated P19 cells....
NeuN (Neuronal Nuclei) is a neuron-specific nuclear protein that has recently been identified as Fox-3/Rbfox3, a member of the Fox-1 family of transcription factors. NeuN is only expressed in the nuclei of differentiated neurons. In some neurons - Purkinje cells, sympathetic ganglion cells, ...
Neuronal nuclear protein (NeuN) is present in roughly half of suprachiasmatic nucleus (SCN) neurons. Their distribution is unique among all neuronal phenotypes described in the SCN. The NeuN-IR does not co-localize with cholecystokinin- or vasoactive intestinal polypeptide-IR. NeuN-IR does co-local...
5) Red nucleus neurons 红核神经元 例句>> 6) internuclear neurons 核间神经元 1. The results were as follows: (1) ABN consisted of two kinds of neurons at least: one was abducent motoneurons(AMNs) and the other was abducent internuclear neurons(AINs). 结果表明 :(1)展神经核至少...
(NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with ...