Decreased number of NeuN-positive neurons in the hippocampi of Rereom/eyes3 embryos.Bum, Jun KimHitisha, P. ZaveriOleg, A. ShchelochkovZhiyin, YuAndrés, HernándezGarcíaMichelle, L. SeymourJohn, S. OghalaiFred, A. PereiraDavid, W. Stockton...
(2011) measured potential toxicity to neurons and glia, and the impact of drug treatments on cell proliferation in several brain regions. NeuN was used as a neural marker, GFAP as a glial marker, and BrdU as a marker of proliferation. The number of NeuN-positive cells in the dentate gyrus...
NeuN is exclusively present in post-mitotic neurons and is absent from neural progenitors, oligodendrocytes, astrocytes, and glia (PMID: 1483388). Involvement in disease · NeuN cytoplasmic localization is increased in the neurons of patients with HIV-associated neurocognitive disorders (PMID: 24215932...
Positive FC (Intra) detected inU-87 MG cells Recommended dilution ApplicationDilution Western Blot (WB)WB : 1:2000-1:10000 Immunohistochemistry (IHC)IHC : 1:10000-1:40000 Immunofluorescence (IF)-PIF-P : 1:50-1:500 Flow Cytometry (FC) (INTRA)FC (INTRA) : 0.20 ug per 10^6 cells in ...
Anti-NeuN stains exclusively neuronal cells in the central and peripheral nervous systems, especially postmitotic and differentiating neurons, as well as terminally differentiated neurons. Anti-NeuN has been used widely as a reliable tool to detect most postmitotic neuronal cell types. The ...
Anti-NeuN stains exclusively neuronal cells in the central and peripheral nervous systems, especially postmitotic and differentiating neurons, as well as terminally differentiated neurons. Anti-NeuN has been used widely as a reliable tool to detect most postmitotic neuronal cell types. The ...
immunoreactivity is first observed shortly after neurons have become postmitotic, no staining has been observed in proliferative zones. The immunohistochemical staining is primarily localized in the nucleus of the neurons with lighter staining in the cytoplasm. The few cell types not reactive with MAB37...
Background:NeuN protein (the neuronal nuclear protein) is a well-recognized marker of post-mitotic neurons, and is highly conserved during evolution. It has been widely used to assess the differentiation state of neurons during development for more than 20 years [1]. NeuN is also known as RB...
We report here immunocytochemical studies of NeuN protein expression in neurons in the substantia nigra (SN) of the human brain ( n = 14, age 27–78 years). Weak positive reactions for NeuN protein were seen in some SN neurons, while other neurons were negative. Overall, reactions for NeuN...
It has been widely used to assess the differentiation state of neurons during development for more than 20 years [1]. NeuN is also known as RBFOX3, a pre-mRNA alternative splicing regulator [2, 3]. Rbfox3 homozygous mutant mice exhibit reduced brain weight, increased susceptibility to ...