Furthermore, the co-localization of BrdU with NeuN in the dentate gyrus in vivo confirmed that the proliferating cells differentiate into neurons [133]. Recently a shorter VGF peptide, TLQP-21, was shown to prevent cerebellar granule cell death induced by serum and potassium deprivation in a ...
NeuN (Neuronal Nuclei) is a neuron-specific nuclear protein that has recently been identified as Fox-3/Rbfox3, a member of the Fox-1 family of transcription factors.NeuN is only expressed in the nuclei of differentiated neurons. In some neurons - Purkinje cells, sympathetic ganglion cells, ...
Normally, the immune response of the antibody is transiently observed only in the mitotic period of neuronal cells, whereas NeuN is not expressed during cell proliferation. NeuN is a very good reference, expressed in mature neurons and retinoic acid-stimulated P19 cells....
Purification:The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen Concentration:1 mg/ml Storage&Stability:-20°C/1 year Subcellular Location:Nucleus Cytoplasm Largely restricted to neuronal nuclei However, significant cytoplasmic localization in neurons from ...
(NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with ...
Using morphometric and densitometric analysis, we demonstrated that all the neurons of interest share a striking feature, namely an extremely low level of cytoplasmic NeuN immunolabeling against a high level of nuclear immunolabeling of this neuronal nuclear antigen, commonly used...
Anti-NeuN stains exclusively neuronal cells in the central and peripheral nervous systems, especially postmitotic and differentiating neurons, as well as terminally differentiated neurons. Anti-NeuN has been used widely as a reliable tool to detect most postmitotic neuronal cell types. The ...
NeuN (Neuronal Nuclei) is a neuron-specific nuclear protein that has recently been identified as Fox-3/Rbfox3, a member of the Fox-1 family of transcription factors. NeuN is only expressed in the nuclei of differentiated neurons. In some neurons - Purkinje cells, sympathetic ganglion cells, ...
NeuN is exclusively present in post-mitotic neurons and is absent from neural progenitors, oligodendrocytes, astrocytes, and glia (PMID: 1483388). Involvement in disease ·NeuN cytoplasmic localization is increased in the neurons of patients with HIV-associated neurocognitive disorders (PMID: 24215932)....
(NeuN, Fox-3, RBFOX3) is a nuclear protein expressed in most post-mitotic neurons of the central and peripheral nervous systems. NeuN is not detected in Purkinje cells, sympathetic ganglion cells, Cajal-Retzius cells, INL retinal cells, inferior olivary, and dentate nucleus neurons. This ...