BRCA1/2 mutations occurred in 6.6% of patients with human epidermal growth factor receptor 2 (HER2/neu)‐positive breast cancer. However, BRCA mutation status did not affect survival outcomes in patients who had HER2/neu‐positive breast cancer....
However, the results clearly indicated that Her2/neu- positive breast cancer cell lines responded uniquely when compared with cell lines that expressed low levels of Her2/neu. For example, Her2/neu-positive tumors were more sensitive to treatment with QLT0267. The 6344 ILK inhibition suppresses ...
Prevalence and Significance of HER-2/neu Amplification in Epithelial Ovarian Cancer AKT2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival. Oncogene 2002; ... Wong,Y.,F.,... - 《Gynecologic & Obstetric Investigati...
We thus rationalized that due to its bone marrow tropism, B19 could be an attractive candidate for targeted gene delivery therapies to bone marrow-resident cells, such as metastatic HER2-positive, breast cancer cells, particularly if its primary cellular receptor binding site is replaced by the ...
MD Pegram,G Pauletti,DJ Slamon - 《Breast Cancer Research & Treatment》 被引量: 703发表: 1998年 HER-2/neu expression in primary and metastatic breast cancer IntroductionTrastuzumab is a highly effective therapy for the treatment of HER-2/neu positive breast cancer. To maximize benefit and minim...
1. Cost Utility of Sequential Adjuvant Trastuzumab for HER2/Neu-Positive Breast Cancer. [J] . Reed SD, Schulman KA Value in health: the journal of the International Society for Pharmacoeconomics and Outcomes Research . 2009,第5期 机译:HER2 / Neu阳性乳腺癌序贯辅助曲妥珠单抗的成本效用。 2. ...
Appl her2-positive breast cancer: a systematic review and Immunohistochem Mol Morphol 2006;14:103–108. cost-effectiveness analysis. CMAJ 2007;176:1429–1434. 18 Rossi S, Laurino L, Furlanetto A, et al. Rabbit 29 Egervari K, Szollosi Z, Nemes Z. Immunohistochemical monoclonal antibodies: a...
HER-2/neu expression in primary and metastatic breast cancer Introduction Trastuzumab is a highly effective therapy for the treatment of HER-2/neu positive breast cancer. To maximize benefit and minimize unnecessary ... EE Lower,E Glass,BS Harman - 《Breast Cancer Research & Treatment》 被引量...
We analyzed the activity of ADCC and antibody-dependent cell-mediated phagocytosis (ADCP) of peripheral blood mononuclear cells (PBMCs) from human epidermal growth factor receptor 2 (HER2/neu) positive breast cancer patients receiving trastuzumab therapy either in an adjuvant (n = 13) or metastatic...
effect of AdVHER-2 on anti-HER-2/neu antibody therapy for well-established breast tumor in transgenic FVBneuN mice, and this combinatorial immunotherapy of trastuzumab with AdVHER-2 vaccine may be used as a new therapeutic strategy for treatment of advanced HER-2/neu-positive breast cancer. ...