Loss or decreases in CD10 expression have been reported in a variety of malignancies (PMID: 16054017). 实验方案 Product Specific Protocols FC protocol for Neprilysin/CD10 antibody 98116-1-RR Download protocol Standard Protocols Click here to view our Standard Protocols ...
Loss or decreases in CD10 expression have been reported in a variety of malignancies (PMID: 16054017). Protocols Product Specific Protocols WB protocol for Neprilysin/CD10 antibody 23898-1-AP Download protocol IHC protocol for Neprilysin/CD10 antibody 23898-1-AP Download protocol IF protocol for ...
recurrently observed in knockdown animals, with individual periods lasting up to 4.500 ms (Fig.1Cand Supplementary Movie4). Prolonged HPs were also characteristic for increasednep4expression, yet to an even stronger extent (individual HP > 20.000 ms, Fig.1Cand Supplementary Movie2). ...
CD10 expression was evaluated in both adipocytes and in surrounding stromal cells. The hibernomas occurred in 28 males and 20 females, ranging from 11-76 years of age and involved the extremities (n=25), pelvis (n=7), abdomen/pelvis/retroperitoneum (n=7), head and neck region (n=6),...
The Human MME solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then ad...
and follicular germinal center lymphomas, immature B cells with in adult bone marrow and on cells from patients with chronic myelocytic leukemia (CML). CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney ...
The matrix metalloproteases (MMPs) are a family of related matrix-degrading enzymes that are important in tissue remodeling and repair during development and inflammation. Abnormal expression is associated with various diseases such as tumor invasiveness, arthritis, and atherosclerosis. MMP activity may al...
Design of the three recombinant proteins.AsNEP-scFc-scFv8D3, where the soluble (extracellular domain) of NEP is recombinantly linked to a scFc of mouse IgG2c antibody. The scFc is then linked to scFv8D3 (BBB transporter).BmuNEP-scFc-scFv8D3, where a mutated variant of NEP (having hi...
evidence that expression levels of neprilysin are decreased in the hippocampus and cerebral cortex of AD patients from the early stages of disease development and also with aging in humans, as well as mice, suggests a close association of neprilysin with the etiology and pathogenesis of AD2. Inde...
Cells were then incu- bated in permeabilization buffer (0.1% Triton X-100 in 0.1% sodium citrate) for 2 min on ice. An additional round of washing and centrifugation was performed before incu- bating the cells with anti-NEP antibody (Merck-Millipore; 1:200) in PBS for 25 min at 4 °...