The CDP produced negative inotropic and chronotropic actions on isolated frog heart. The pharmacological effect was selectively inhibited by atropine indicating that these might have been mediated through muscarinic receptor.ShabiDepartmentM.Department
In conclusion, CDCA and DCA induced positive inotropic effects by elevating the Ca 2+ in left ventricular myocytes. They exerted negative chronotropic effects by lowering the pace of the sinoatrial node in rat heart. These results indicated that the potential role of bile acids in cardiopathy ...
The weakening by pertussis toxin of the negative inotropic effect of carbamoylcholine is probably mainly due to the ADP ribosylation of the Gi regulatory protein and the subsequent loss of influence of muscarinic receptors on adenylate cyclase. The blockade of the negative chronotropic action of ...
Higenamine (HG) is a natural benzylisoquinoline alkaloid isolated from with positive inotropic and chronotropic effects. This study aimed to investigate t... J Wen,L Zhang,J Wang,... - 《Journal of Cellular & Molecular Medicine》 被引量: 0发表: 2020年 Anti-Inflammatory and Antioxidative Effect...
Summary Inotropic and chronotropic responsiveness of yellow perch {Perca flavescens Mitchill) and smallmouth bass (Micropterus dolomieui Lace'pede) hearts,... JR Bailey,WR Driedzic - 《Journal of Experimental Biology》 被引量: 81发表: 1990年 A study of the dual innervation of teleost heart by...
4) negative inotropic action 负性变力效应 5) negative chronotropic action 负性变时效应 6) conduction effect 传导效应 1. An Analysis on Formation Mechanism of Audit Opinion and Market Conduction Effect; 审计意见的形成机制与市场传导效应分析
Acetylcholine (ACh) of the parasympathetic nervous system exerts a direct negative chronotropic effect on the sinoatrial nodal tissue, a negative dromotropic effect on atrio-ventricular conduction and a direct negative inotropic effect on the atria. Furthermore ACh has an indirect negative inotropic effe...
Inhibitory Effect of Aqueous and Ethanolic Garlic (Allium sativum L., Lilliaceae) Extracts on the Rat Atria The acute negative inotropic and chronotrophic effects of aqueous and alcoholic garlic extracts (Allium sativum L.) on spontaneous and adrenalin-stimulated... Mirjana,Radenkovic,Suzana,... ...
increased myocardial contractility without chronotropic effect in ratsExtracellular matrix and fibrosis - Vascular339Ablation of Toll-like receptor 9 causes cardiac rupture after myocardial infarction by attenuating proliferation and differentiation of cardiac fibroblasts340Altered vascular remodeling in the mouse ...
Vahlensieck U, Bokn´ik P, Knapp J, Linck B, Mu¨ ller FU, Neumann J, Herzig S, Schlu¨ ter H, Zidek W, Deng MC, Scheld HH and Schmitz W (1996) Negative chronotropic and inotropic effects exerted by diadenosine hexaphophate (Ap6A) via A1-adenosine receptors. Br J Pharmacol 119...