Anatomy of a negative feedback loop: the case of IkappaBalpha. J R Soc Interface. 2015;12:0262.Fagerlund, R. et al. Anatomy of a negative feedback loop: the case of Ikappa- Balpha. J. R. Soc. Interface 12, 0262
Another example of negative feedback occurs when your body's temperature begins to rise and a negative feedback response works to counteract and stop the rise in temperature. Sweating is a good example ofnegative feedback. What is feedback inhibition simple definition? Feedback inhibition, in enz...
Neurons in sensory systems often pool inputs over arrays of presynaptic cells, giving rise to functional subunits inside a neuron’s receptive field. The organization of these subunits provides a signature of the neuron’s presynaptic functional connecti
The tubules include the proximal convoluted tubule, the loop of Henle, the distal convoluted tubule, and the collecting duct. The nephrons contained in the cortex layer of the kidney are distinct from the anatomy of those contained in the medulla. The principal difference is the length of the...
Overall, our study unveiled the underlying molecular mechanism by which miR-489 regulates an estrogen signaling pathway through a negative feedback loop and uncovered its role in both the development of and overcoming of tamoxifen resistance in breast cancers. Keywords: miR-489; breast cancer; ...
We posit that the physiological function of the negative feedback loop between ERα and the miR-489 would be a fail-safe mechanism to avoid high ERα activity. High ERα activity is potentially dangerous for the cell and is a major risk factor for breast cancer. In addition, miR-489 coul...