Anatomy of a negative feedback loop: the case of IkappaBalpha. J R Soc Interface. 2015;12:0262.Fagerlund, R. et al. Anatomy of a negative feedback loop: the case of Ikappa- Balpha. J. R. Soc. Interface 12, 0262 (2015).
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Neurons in sensory systems often pool inputs over arrays of presynaptic cells, giving rise to functional subunits inside a neuron’s receptive field. The organization of these subunits provides a signature of the neuron’s presynaptic functional connecti
Overall, our study unveiled the underlying molecular mechanism by which miR-489 regulates an estrogen signaling pathway through a negative feedback loop and uncovered its role in both the development of and overcoming of tamoxifen resistance in breast cancers. Keywords: miR-489; breast cancer; ...