Testosterone may have deleterious effects on cognitive function in older Caucasian men with high oxidative stress (OS), but may be beneficial under conditions of low OS. This is one of the findings of a US study
Basrur . (1978) Effects of testosterone on the testes of sexually quiescent pheasants: Evidence for a negative feedback mechanism. British Poultry Science 19 , 709-712 Online publication date: 1-Nov-1978. /Purohit VD, Basrur PK. Effects of testosterone on the testes of sexually quiescent ...
Exercise training in postmenopausal women seems to have additive or synergistic effects with estrogen replacement therapy to increase bone mineral density. Exercise may stimulate release of insulin-like growth factor-1, testosterone, and growth hormone, which increase bone formation leading to enhanced ...
22 The incidence of secondary osteoporosis with excessive GC is well described and recognized in the literature;22–24 however, the mechanisms of GC action are less understood. The primary source of GC-induced bone loss is thought to be direct inhibitory effects on osteoblast activity.23 As the...
The infertility of the gilt presented here, before unilateral gonadectomy, was most likely due to the effects of testosterone, generating negative feedback on the estrous cycle. This case demonstrates the feasibility of achieving pregnancy in an animal with gonadal disorders of sexual development. ...
[19]. The infertility of the gilt presented here, before unilateral gonadectomy, was most likely due to the effects of testosterone, generating negative feedback on the estrous cycle. This case demonstrates the feasibility of achieving pregnancy in an animal with gonadal disorders of sexual ...
Negative effects of ketoprofen and meloxicam on distal cauda epidydimal duct contractions, testosterone levels, and sperm count in rats Reproductive Biology Volume 24, Issue 4, December 2024, Page 100963 Purchase options CorporateFor R&D professionals working in corporate organizations. Academic and perso...
Previous work by our group, among others, has shown that with the exception of oestradiol it is not the classic hormones that achieve many of the CNS effects. Instead, the 3alpha-hydroxy-5alpha/beta metabolites of progesterone (pregnanolone and allopregnanolone), testosterone (3alpha-5alpha-...
Strategies that interfere with the binding of the receptor programmed cell death protein-1 (PD-1) to programmed death ligand-1 (PD-L1) have shown marked efficacy against many advanced cancers, including those that are negative for PD-L1. Precisely why pa
In the experiment with hormone replacement therapy, if a hormone such as testosterone were used in place of estrogen, what effects would be seen? When it is hot, they sweat, but when it is cold, it begins to shiver. What type of feedback is this? Negative or positive? What...