The 18-gene 10-year signature was internally validated in the TransATAC validation set, showing prognostic information similar to that of Oncotype DX Recurrence Score, PAM50 risk of recurrence score, Breast Cancer Index and IHC4 (score based on four IHC markers), as well as in the external ...
When the Plus Sign is a Negative: Challenging and Reinforcing Embodied Stigmas Through Outliers and Counter-Narrativesstigmacounter-narrativesidentityWhen individuals become aware of their stigma, they attempt to manage their identity through discourses that both challenge and reinforce power. Identity ...
4. Discussion Our results demonstrate that using hospitalized patients with ARI who test negative for SARS-CoV-2 (test-negative controls) and hospitalized patients without ARI (syndrome-negative controls) as control groups to estimate COVID-19 vaccine effectiveness produced very similar estimates of VE...
The effect of abemaciclib plus fulvestrant on overall survival in hormone receptor-positive, ERBB2-negative breast cancer that progressed on endocrine therapy-MONARCH 2: a randomized clinical trial. JAMA Oncol. 6, 116–124 (2020). PubMed Google Scholar Turner, N. C. et al. Overall survival ...
Fig. 4: In vivo efficacy study of pevonedistat. Tumor volume growth curves for individual PDX models treated either with vehicle (black) or pevonedistat (red). Statistical significance denoted under the PDX_ID, was determined using a two-way ANOVA applied to the time series. Arrows connect...
Briefly, each cell pellet was resuspended in 10 ml of the column buffer (20 mM Tris-HCl, pH 8.0; 200 mM NaCl; 1 mM EDTA) plus 1 mM PMSF, incubated on ice for 20 min, sonicated, centrifuged and the supernatant was added to 2 ml of amylose resin slurry. After washing six times ...
4 −7.466 II 12 22 22 12 III 11 54 52 13 Lymph node metastasis 0-4 17 28 −16.986 0.028▲* 31 22 −10.405 5-8 6 33 29 5 ≥9 3 18 16 2 Relapse No 23 44 9.094 0.002 41 26 −11.590 Yes 3 35 *means P < 0.05; − means χ2 of Fisher exact test; ▲means P ...
Transcriptome data were acquired from GSE36133 (Cancer Cell Line Encyclopedia project (CCLE)) for 20 TNBC cell lines using the Affymetrix Human Genome U133 Plus 2.0 Array platform. The fragments per kilobase million (FPKM) values of RNA sequencing data were converted into transcripts per kilobase...
Table 4. Generalized linear mixed models of maternal sleep quality across gestation and neonatal uncinate fasciculus covarying for prenatal stressful life events, anxiety, and depression. Fixed effectsLeft UncinateRight Uncinate b estimateSETb estimateSET Empty Cell Model 1: Prenatal Stressful Life Events...
Canc Netw. 18, 452–478 (2020). Article CAS PubMed Google Scholar Schmid, P. et al. Atezolizumab plus nab-paclitaxel as first-line treatment for unresectable, locally advanced or metastatic triple-negative breast cancer (IMpassion130): updated efficacy results from a randomised, double-blind,...