When the Plus Sign is a Negative: Challenging and Reinforcing Embodied Stigmas Through Outliers and Counter-Narrativesstigmacounter-narrativesidentityWhen individuals become aware of their stigma, they attempt to manage their identity through discourses that both challenge and reinforce power. Identity ...
That’s especially true of gambling. It’s a “silent addiction” for which the individual tends to hide, and the loved ones will often enable to protect the person, often resulting in worse implications for the one suffering the disorder plus everyone associated with that person sometimes. But...
The prespecified subgroup analysis showed a consistent response in patients with ECOG performance status (PS) of 1 (17/73, 23.3%), metastatic organs ≥4 (7/24, 29.2%) and presence of CNS metastasis (2/8, 25.0%; Supplementary Fig. 2). Given the suboptimal response (objective response rate...
Polyaniline–Fe3O4 nanocomposite with and without ionic liquid were successfully synthesized via in situ polymerization using cetyl trimethylammonium bromide (CTAB) as surfactant. Both TG analysis and FT-IR measurements proved the presence of organic layer on the surface of Fe3O4 nanoparticles. The...
The 2.5th and 97.5th percentiles TSH were 0.32 mU/l and 5.06 mU/l respectively. The mean±SD and median (IQR) for FT4 for all negative TPOAb subjects were 1.19±0.16 and 1.18 (1.08–1.31) ng/dl respectively. Conclusion: Reference ranges for thyroid function tests need to be derived fro...
OPEN SUBJECT AREAS: EMBRYONIC STEM CELLS CELL GROWTH Nr0b1 is a negative regulator of Zscan4c in mouse embryonic stem cells Setsuko Fujii1,4, Satomi Nishikawa-Torikai1,4, Yoko Futatsugi1, Yayoi Toyooka1,2, Mariko Yamane1, Satoshi Ohtsuka1 & Hitoshi Niwa1,3,4 Received 24 September 2014...
In the dose-escalation assessment, the tolerability and safety of balixafortide plus eribulin were acceptable and similar to monotherapy with eribulin or balixafortide. In addition, the development of a receptor-based peptide, a CXCR4-binding peptide (DV1), has been shown to be associated ...
Nectin-4 expression levels of breast cancer cells (MDA-MB-468: TNBC cells; and MCF-7, non-TNBC cells) were proved by western blot, flow cytometry, and immunofluorescence imagning. Cell uptake assays, SPECT imaging, and biodistribution were performed to evaluate Nectin-4 targeting of 99mTc-HYNI...
5 × 104 cells were seeded on 24 well modified Boyden chambers coated with Matrigel (Corning, New York, U.S. 1 mg/ml) without serum for invasion or without Matrigel for migration. The chambers were then put on 24-well plate contained DMEM plus 20% FBS for 12 h at 37 °...
Philadelphia chromosome–negative B-cell acute lymphoblastic leukemia (Ph-negative B-ALL) is the most common type of adult ALL [1]. Recent high-intensity chemotherapy regimens have improved the survival outcome of adult patients with Ph-negative B-ALL 2, 3, 4, 5. There is no consensus on ...