Nectin-4 基因功能 This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type...
"Nectin-4 and p95-ErbB2 cooperatively regulate Hippo signaling-dependent SOX2 gene expression, enhancing anchorage-independent T47D cell proliferation." Scientific Reports 11.1 (2021): 7344.[7] Sethy, Chinmayee, et al. "Nectin-4 promotes lymphangiogenesis and lymphatic metastasis in breast cancer by...
Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation...
The present invention also features a method that includes double-stranded molecules against -4 gene nectin, vectors encoding them, the step of administering to the subject thereof and compositions containing them, are to treat or prevent cancer it is useful for. Also disclosed are methods of ...
Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation...
描述:Recombinant Human Nectin-4 is produced by our Mammalian expression system and the target gene encoding Gly31-Val351 is expressed with a 6His tag at the C-terminus. Accession:Q96NY8 中文别名:Nectin-4蛋白; PVRL4蛋白 来源:Human Cells ...
Also, disclosed are methods of identifying candidate compounds for treating and preventing cancer, using the Nectin-4 polypeptide or cells expressing the Nectin-4 gene.doi:EP2373794 A1Yusuke NakamuraYataro DaigoTakuya TsunodaYoshiro KishiYoshihiro Fujii...
Expressed gene:hNectin4 Stability:32 passages Freeze Medium:90% FBS+10% DMSO Culture Medium:DMEM+10%FBS+2ug/ml puromycin Mycoplasma Testing:Negative Storage:Liquid nitrogen III. Description of Host Cell Line Organism:Mouse Tissue:Colon Morphology:Epitheloid cell ...
Nectin-4 (NCBI Gene ID: 81607) has been reported as a cancer biomarker as it is expressed in cancer tissues (eg. ovary, breast, lung, bladder and cervical) and cancer cell lines but not in normal cells (Derycke et al., 2010, Fabre-Lafay et al., 2005, Takano et al., 2009). ...
Nectin-4, also known as Poliovirus receptor-related protein 4 (Gene name: PVRL4), is a 66-kDa type I transmembrane glycoprotein belonging to the Nectin immunoglobulin superfamily (1). The Latin wordnectomeans "to connect", indicating the role of nectins in Ca2+‑independent cell-cell adhesi...