有研究表明,在角质形成细胞恶性转化的早期阶段,迁移细胞的前进边沿的Nectin-1水平降低,表明Nectin-1在减少细胞-细胞粘附以及增加侵袭性和转移方面的作用。Nectin-1也称为CD111,CD111与CD96相互作用调节NK细胞和T细胞功能。 图2:Necitn家族成员结构...
Nectin-1也称为CD111,CD111与CD96相互作用调节NK细胞和T细胞功能。 图2:Necitn家族成员结构模式图 Necitin-2是典型Nectin蛋白,它可以与Nectin家族蛋白相互作用介导细胞-细胞粘附;与免疫受体CD226和TIGIT结合,以调节免疫功能;与病毒糖蛋白相互作用,作为单纯疱疹病入侵宿主的受体。Nectin-2在正常细胞中表达,但是在胆囊...
因CD111/NECTIN1重组蛋白/CD111/NECTIN1 Recombinant Protein产品的序列过长,详情查看产品说明书 来源宿主 E.coli 溶解建议 PBS, 4M Urea, PH7.4 保存建议 Store at 4 其他 Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋...
Here, we review the role of DNAM-1, TIGIT and CD96 in NK cell biology summarizing the recent advances made on the role of these receptors in various pathologies, such as cancer, viral infections and autoimmunity.doi:10.1038/icb.2013.95Lucas Ferrari de Andrade...
Although the mode of interaction of TIGIT and CD96 with their cognate ligands has been established (29, 3031), the structural basis for human DNAM-1 ligand recognition is unknown. To address this gap in our knowledge, we expressed the extracellular Ig domains of human DNAM-1 (D1–D2) ...
CD226／CD112(DNAM-1／NECTIN-2)对肥大细胞的协同刺激 维普资讯 http://www.cqvip.com
CD spectra were obtained at 15 μM peptide concentration, for Protonectin, Protonectin (1–6) and a mixture 1:1 (mol/mol) of both, in different environments: 40% (v/v) 2,2,2-trifluoroethanol trifluoroethanol (TFE)/bi-distilled water and sodium dodecyl sulfate solutions (8 mM and 165 ...
These receptors binding nectin and necls proteins include DNAM-1 (CD226, TLiSA-1, PTA1), CD96 (TACTILE), TIGIT (WUCAM, VSTM3), and CRTAM and were shown to impact the functions of diverse immune cell types including natural ... L Martinet,MJ Smyth - 《Encyclopedia of Immunobiology》 ...