Figure: Live cell detection of mitochondrial membrane potential, caspase activity, and apoptosis in MCF-7 breast cancer cells. Untreated MCF-7 cells (86012803) (A) or treated with staurosporine (S5921) overnight to induce apoptosis (B), then stained with the BioTracker™ 405 Blue Mitochondria ...
In this lesson, you're going to learn about two of the major ways by which cells die. One is called 'necrosis' and the other 'apoptosis'. The lesson will explain the differences between these two processes. Cell Death The cells of your body can die in numerous ways. They can be kil...
Apoptosis and Necrosis in Livers of Fischer-344 Rats and Sex Differences in Damage by Reactive Oxygen SpeciesCells, CulturedAnimalsCricetulusOxygenMelphalanNitroimidazolesMisonidazoleMetyraponeDexamethasoneGlutathionePediatric Research publishes original papers, invited reviews, and commentaries on the etiologies ...
apoptotic and necrotic cell death;9 in the pancreatic acinar cell, oscillatory global rises of cytosolic Ca2 þ may induce apoptosis,10 while sustained elevations promote necrosis.11,12 These differences may relate to effects on mitochondrial function associated with the respective Ca2 þ signals. ...
Cell Death, Apoptosis, and Autophagy in Retinal Injury Michael E.Boulton, ...William A.DunnJr, inRetina (Fifth Edition), 2013 Necrosis Necrosishas been defined as a type of uncontrolled cell death that can occur in response to infection, toxins, chemicals,injury, or lack ofblood supply.2,...
There is growing evidence that necrosis, instead ofapoptosis, could act as a natural adjuvant, which could activate an immune response. In this work we have investigated if induction oftumor necrosiscould trigger the affluence ofinflammatory cellsat the tumor site, and thus induce an immune respons...
**p < 0.01 vs. untreated control group. #p < 0.01 compared with the corresponding group Full size image SKO treatment significantly increased the auto-secretion of TNF-α to induce cell apoptosis and necrosis To further understand the role and corresponding mechanisms of RIP1 in SKO ...
It has been reported that TNFa can inhibit the proliferation and induce apoptosis of A549 cells, besides, the concentration of IL-1β and IL-8 in cell supernatant will increase after stimulation. Therefore, a stimulation assay of TNFa was conducted using A549 cells. Briefly, A549 cells were ...
Since the discovery of cell apoptosis, other gene-regulated cell deaths are gradually appreciated, including pyroptosis, ferroptosis, and necroptosis. Necroptosis is, so far, one of the best-characterized regulated necrosis. In response to diverse stimul
apoptosis than Trpc3 expressing cells. The questions remained (a) whether the plaque phenotype in transplanted mice resulted from a genuine effect of Trpc3 on macrophages, and (b) whether the reduced necrosis and macrophage apoptosis in plaques of these mice was a manifestation of the selective ...