典型的NLR蛋白一般包括三个结构域,根据N端结构域的特异性NLR蛋白主要分为TNL(TIR-NBS-LRR)和CNL(CC-NBS-LRR)两类。近两年的研究还发现ETI免疫反应的激活需要两类N端特异的NLR蛋白RNL(CCR-NBS-LRR)作为助手(helper),包括NRG1 (N REQUIREMENT GENE 1)和ADR1(ACTIVATED DISEASE RESISTANCE 1)家族(Dong et al....
nlr突变表现共分离,说明 rwt3 nlr候选基因与无毒基因 pwt3诱发的抗病性有关。 rwt4的候选 nlr基因附近包含一个小麦串联激酶基因( wtk ),该基因是抗白粉病基因 pm24的等位基因,因此作者将 wtk和 nlr基因均作为 rwt4的候选基因。采取...
NLR蛋白通常包括三个结构域，根据N端结构域的特异性，可分为TNL(TIR-NBS-LRR)和CNL(CC-NBS-LRR)两类。近年来，研究发现ETI免疫反应的激活需要RNL (CCR-NBS-LRR)家族成员，如NRG1和ADR1，作为助手。
Gene structures were compared, and gene expression was profiled across different NLR subfamilies. Additionally, in vitro leaf inoculation assays with Botrytis cinerea were performed to assess the resistance of various strawberry species. Results: Our analysis revealed that non-TN...
植物中常与LRR结构域串联形成NLR免疫受体,哺乳动物则多与CARD、PYD等结构域组合参与炎症小体组装。这种结构域组合差异反映出进化压力下的功能特化,比如水稻抗稻瘟病蛋白Pikp的nbs结构域与重金属结合结构域融合,形成独特的重金属离子感应机制。这种结构创新为农作物抗病育种提供了新思路。 现有研究存在三个关键盲点。第...
and transcriptional reprogramming45. Many DEGs related to most of these elements were identified inMrRPV1-transgenic Shiraz. Because most of these elements are shared between PRR and NLR signaling, the zigzag model of the plant immune system defined a threshold for the activation of HR2rather than...
W. Recent Advances in Plant NLRStructure, Function, Localization, and Signaling. Front. Immunol. 4, (2013). Inoue, H. et al. Blast resistance of CC-NB-LRR protein Pb1 is mediated by WRKY45 through protein-protein interaction. Proc. Natl. Acad. Sci. USA 110, 9577–9582 (2013). ...
Wang L, Zhao L, Zhang X, Zhang Q, Jia Y, Wang G, Li S, Tian D, Li W, Yang S (2019) Large-scale identification and functional analysis of NLR genes in blast resistance in the Tetep rice genome sequence. Proc Natl Acad Sci 116:18479–18487 CAS PubMed PubMed Central Google Scholar...
We reported an NBS-LRR gene, PsoRPM3, is highly expressed following RKN infection, initiating an HR response that promotes plant resistance. Meloidogyne sp
根据NLR-Annotator论文,其中完整的NLR基因是由三部分组成的,所以TIR-NBARC-LRR或CC-NBARC-LRR的结构的是完整NLR基因。 Steuernagel B, Witek K, Krattinger SG, Ramirez-Gonzalez RH, Schoonbeek HJ, Yu G, Baggs E, Witek AI, Yadav I, Krasileva KV, Jones JDG, Uauy C, Keller B, Ridout CJ, Wul...