Researchers have used artificial-intelligence models to create regulatory DNA sequences that drive gene expression in specific cell types. Such synthetic sequences could be used to target gene therapies to particular cell populations. Andreas R. Pfenning ...
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The bile acid membrane receptor TGR5: a valuable metabolic target. Dig. Dis. 29, 37–44 (2011). Article PubMed PubMed Central Google Scholar Staels, B. & Fonseca, V. A. Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration. Diabetes Care 32, ...
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On the basis of trends in the most recent years, we project these estimates to the years 2025 and 2030, and determine the probability of meeting the WHO GNTs of ≥50% and ≥70% EBF prevalence in the respective target years. Furthermore, we examine relative and absolute subnational ...