In this Perspective, Wahida et al. consider six riddles in precision oncology that must be solved to achieve better clinical responses to molecular targeted therapies. Adam Wahida Lars Buschhorn Razelle Kurzrock Perspective24 Nov 2022 Targeting the gut microbiota for cancer therapy ...
A single-cell tumor immune atlas for precision oncology. Genome Res 31, 1913–1926 (2021). Article PubMed PubMed Central Google Scholar He, P. et al. The changing mouse embryo transcriptome at whole tissue and single-cell resolution. Nature 583, 760–767 (2020). Article ADS CAS PubMed...
Remarkable progress has been made in the development of biomarker-driven targeted therapies for patients with multiple cancer types, including melanoma, breast and lung tumours, although precision oncology for patients with colorectal cancer (CRC) continues to lag behind. Nonetheless, the availability of...
selecting for the molecular drivers of a patient’s cancer. Pediatric precision oncology studies have identified potentially targetable molecular findings in over 65% of children with high-risk cancers1,2,3,4,5. However, clinical uptake of
724 Journal Impact Factor 223.679 74.449 70.670 59.102 57.618 54.301 54.000 51.848 51.273 44.019 43.704 43.351 43.070 41.037 40.443 38.887 38.296 36.216 35.386 34.648 34.106 34.024 34.024 33.407 33.250 33.162 33.069 32.274 31.864 31.583 30.641 30.628 28.755 28.467 28.295 28.245 27.778 27.604 27.516 26.922 ...
oncology, including Lancet Oncology, JAMA Oncology, Cancer Cell, Nature sub-journals, Journal of Thoracic Oncology, etc. The total impact factor of these articles exceeds 500. He serves as the principal investigator of a sub-project of the National 973 Project, the leader of the National Key ...
documents published in that journal. The chart shows the evolution of the average number of times documents published in a journal in the past two, three and four years have been cited in the current year. The two years line is equivalent to journal impact factor ™ (Thomson Reuters) ...
Over the next 25 years, genomic-driven analysis will continue to broaden the impact of personalized medicine in healthcare globally. Precision medicine will continue to deliver its new paradigm in cancer care and reach more patients. Immunotherapy will deliver on its promise to dismantle cancer’s ...
oncology, including Lancet Oncology, JAMA Oncology, Cancer Cell, Nature sub-journals, Journal of Thoracic Oncology, etc. The total impact factor of these articles exceeds 500. He serves as the principal investigator of a sub-project of the National 973 Project, the leader of the National Key ...
Using clinico-genomic data from 78,287 cancer patients, this study identifies genomic alterations linked to survival outcomes, advancing precision oncology by predicting responses to immunotherapy, chemotherapy, and targeted therapies across 20 cancers. ...