Nature Biotechnology volume 36, pages 258–264 (2018)Cite this article 83k Accesses 1313 Altmetric Metrics details Abstract Nanoscale robots have potential as intelligent drug delivery systems that respond to molecular triggers1,2,3,4. Using DNA origami we constructed an autonomous DNA robot ...
定点清除肿瘤局部血小板,扩大血管内皮间隙,从而提高化疗药物的瘤内富集,实现了化疗增效减毒的科学目标(Nature Biomedical Engineering, 2017, 1, 667-679);构建了系列具有临床转化潜力的聚合物智能纳米药物,负载血小板激动剂,实现特异性的肿瘤血管栓塞(Nature Biotechnology,2018, 36, 258-264; Nature Biomedical Engineeri...
Nature Biotechnology volume 36, pages 962–970 (2018)Cite this article 23k Accesses 237 Citations 138 Altmetric Metrics details Abstract Spatially resolved single-cell RNA sequencing (scRNAseq) is a powerful approach for inferring connections between a cell's identity and its position in a tissue....
Public companies continued to ride the crest of the wave of financing, licensing deals and regulatory approvals, but clouds may be looming on the horizon for the biggest biotech players. Chris Morrison and Riku Lähteenmäki report.
(Nature Biomedical Engineering, 2017, 1, 667-679) ;构建了系列具有临床转化潜力的聚合物智能纳米药物,负载血小板激动剂,实现特异性的肿瘤血管栓塞 (Nature Biotechnology,2018, 36, 258-264; Nature Biomedical Engineering, 2020, 4, 732-742) ,或血管生成抑制和化疗联合 (Cancer Research, 2023, 83, 2924-...
NATURE BIOTECHNOLOGY 30 Nature Photonics 31 NATURE MEDICINE 32 Nature Reviews Chemistry 33 LANCET NEUROLOGY 34 NATURE METHODS PHYSICS REPORTS-REVIEW SECTION OF 35 PHYSICS LETTERS 36 JOURNAL OF CLINICAL ONCOLOGY 37 Living Reviews in Relativity 38 BMJ-British Medical Journal 39 LANCET INFECTIOUS DISEASES ...
2,nature biotechnology:大脑情绪解码 来源:思影科技 南加州大学Sani和Shanechi等人在nature biotechnology杂志上发表文章。此研究建立了一个模型框架,用以解码7位癫痫病患者的多处颅内记录的情绪状态变化,这些癫痫病患者在多天内间断性地自我报告情绪状态。该研究建立了情绪状态的动态神经编码模型和每个个体相应的解码器,...
当地时间2019年5月27日,《Nature Biotechnology》公布2018年科研产业化的优秀成果,包括基因治疗、过继性免疫细胞治疗、基因编辑、基于RNA修饰的和未折叠蛋白反应的药物等十大案例。基因慧摘译如下供战略及投融资参考,不尽之处请参考原文。回复“NBT”可获得英文全文PDF。
Nature Biotechnology volume 37, pages 730–743 (2019)Cite this article 17k Accesses 61 Citations 46 Altmetric Metrics details Abstract The combination of modern biotechnologies such as DNA synthesis, λ red recombineering, CRISPR-based editing and next-generation high-throughput sequencing increasingly ...
Letter10 Dec 2018 T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide–MHC complexes The relative affinity of T cell receptors for different peptide–MHCs is measured at high throughput, revealing T cell cross-reactivity. Amalie K Bentz...